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Dr. Carleen Eaton

Dr. Carleen Eaton

The Endocrine System

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Table of Contents

Section 1: Chemistry of Life
Elements, Compounds, and Chemical Bonds

56m 18s

Intro
0:00
Elements
0:09
Elements
0:48
Matter
0:55
Naturally Occurring Elements
1:12
Atomic Number and Atomic Mass
2:39
Compounds
3:06
Molecule
3:07
Compounds
3:14
Examples
3:20
Atoms
4:53
Atoms
4:56
Protons, Neutrons, and Electrons
5:29
Isotopes
10:42
Energy Levels of Electrons
13:01
Electron Shells
13:13
Valence Shell
13:22
Example: Electron Shells and Potential Energy
13:28
Covalent Bonds
19:52
Covalent Bonds
19:54
Examples
20:03
Polar and Nonpolar Covalent Bonds
23:54
Polar Bond
24:07
Nonpolar Bonds
24:17
Examples
24:25
Ionic Bonds
29:04
Ionic Bond, Cations, Anions
29:19
Example: NaCl
29:30
Hydrogen Bond
33:18
Hydrogen Bond
33:20
Chemical Reactions
35:36
Example: Reactants, Products and Chemical Reactions
35:45
Molecular Mass and Molar Concentration
38:45
Avogadro's Number and Mol
39:12
Examples: Molecular Mass and Molarity
42:10
Example 1: Proton, Neutrons and Electrons
47:05
Example 2: Reactants and Products
49:35
Example 3: Bonding
52:39
Example 4: Mass
53:59
Properties of Water

50m 23s

Intro
0:00
Molecular Structure of Water
0:21
Molecular Structure of Water
0:27
Properties of Water
4:30
Cohesive
4:55
Transpiration
5:29
Adhesion
6:20
Surface Tension
7:17
Properties of Water, cont.
9:14
Specific Heat
9:25
High Heat Capacity
13:24
High Heat of Evaporation
16:42
Water as a Solvent
21:13
Solution
21:28
Solvent
21:48
Example: Water as a Solvent
22:22
Acids and Bases
25:40
Example
25:41
pH
36:30
pH Scale: Acidic, Neutral, and Basic
36:35
Example 1: Molecular Structure and Properties of Water
41:18
Example 2: Special Properties of Water
42:53
Example 3: pH Scale
44:46
Example 4: Acids and Bases
46:19
Organic Compounds

53m 54s

Intro
0:00
Organic Compounds
0:09
Organic Compounds
0:11
Inorganic Compounds
0:15
Examples: Organic Compounds
1:15
Isomers
5:52
Isomers
5:55
Structural Isomers
6:23
Geometric Isomers
8:14
Enantiomers
9:55
Functional Groups
12:46
Examples: Functional Groups
12:59
Amino Group
13:51
Carboxyl Group
14:38
Hydroxyl Group
15:22
Methyl Group
16:14
Carbonyl Group
16:30
Phosphate Group
17:51
Carbohydrates
18:26
Carbohydrates
19:07
Example: Monosaccharides
21:12
Carbohydrates, cont.
24:11
Disaccharides, Polysaccharides and Examples
24:21
Lipids
35:52
Examples of Lipids
36:04
Saturated and Unsaturated
38:57
Phospholipids
43:26
Phospholipids
43:29
Example
43:34
Steroids
46:24
Cholesterol
46:28
Example 1: Isomers
48:11
Example 2: Functional Groups
50:45
Example 3: Galactose, Ketose, and Aldehyde Sugar
52:24
Example 4: Class of Molecules
53:06
Nucleic Acids and Proteins

37m 23s

Intro
0:00
Nucleic Acids
0:09
Deoxyribonucleic Acid (DNA) and Ribonucleic Acid (RNA)
0:29
Nucleic Acids, cont.
2:56
Purines
3:10
Pyrimidines
3:32
Double Helix
4:59
Double Helix and Example
5:01
Proteins
12:33
Amino Acids and Polypeptides
12:39
Examples: Amino Acid
13:25
Polypeptide Formation
18:09
Peptide Bonds
18:14
Primary Structure
18:35
Protein Structure
23:19
Secondary Structure
23:22
Alpha Helices and Beta Pleated Sheets
23:34
Protein Structure
25:43
Tertiary Structure
25:44
5 Types of Interaction
26:56
Example 1: Complementary DNA Strand
31:45
Example 2: Differences Between DNA and RNA
33:19
Example 3: Amino Acids
34:32
Example 4: Tertiary Structure of Protein
35:46
Section 2: Cell Structure and Function
Cell Types (Prokaryotic and Eukaryotic)

45m 50s

Intro
0:00
Cell Theory and Cell Types
0:12
Cell Theory
0:13
Prokaryotic and Eukaryotic Cells
0:36
Endosymbiotic Theory
1:13
Study of Cells
4:07
Tools and Techniques
4:08
Light Microscopes
5:08
Light vs. Electron Microscopes: Magnification
5:18
Light vs. Electron Microscopes: Resolution
6:26
Light vs. Electron Microscopes: Specimens
7:53
Electron Microscopes: Transmission and Scanning
8:28
Cell Fractionation
10:01
Cell Fractionation Step 1: Homogenization
10:33
Cell Fractionation Step 2: Spin
11:24
Cell Fractionation Step 3: Differential Centrifugation
11:53
Comparison of Prokaryotic and Eukaryotic Cells
14:12
Prokaryotic vs. Eukaryotic Cells: Domains
14:43
Prokaryotic vs. Eukaryotic Cells: Plasma Membrane
15:40
Prokaryotic vs. Eukaryotic Cells: Cell Walls
16:15
Prokaryotic vs. Eukaryotic Cells: Genetic Materials
16:38
Prokaryotic vs. Eukaryotic Cells: Structures
17:28
Prokaryotic vs. Eukaryotic Cells: Unicellular and Multicellular
18:19
Prokaryotic vs. Eukaryotic Cells: Size
18:31
Plasmids
18:52
Prokaryotic vs. Eukaryotic Cells
19:22
Nucleus
19:24
Organelles
19:48
Cytoskeleton
20:02
Cell Wall
20:35
Ribosomes
20:57
Size
21:37
Comparison of Plant and Animal Cells
22:15
Plasma Membrane
22:55
Plant Cells Only: Cell Walls
23:12
Plant Cells Only: Central Vacuole
25:08
Animal Cells Only: Centrioles
26:40
Animal Cells Only: Lysosomes
27:43
Plant vs. Animal Cells
29:16
Overview of Plant and Animal Cells
29:17
Evidence for the Endosymbiotic Theory
30:52
Characteristics of Mitochondria and Chloroplasts
30:54
Example 1: Prokaryotic vs. Eukaryotic Cells
35:44
Example 2: Endosymbiotic Theory and Evidence
38:38
Example 3: Plant and Animal Cells
41:49
Example 4: Cell Fractionation
43:44
Subcellular Structure

59m 38s

Intro
0:00
Prokaryotic Cells
0:09
Shapes of Prokaryotic Cells
0:22
Cell Wall
1:19
Capsule
3:23
Pili/Fimbria
3:54
Flagella
4:35
Nucleoid
6:16
Plasmid
6:37
Ribosomes
7:09
Eukaryotic Cells (Animal Cell Structure)
8:01
Plasma Membrane
8:13
Microvilli
8:48
Nucleus
9:47
Nucleolus
11:06
Ribosomes: Free and Bound
12:26
Rough Endoplasmic Reticulum (RER)
13:43
Eukaryotic Cells (Animal Cell Structure), cont.
14:51
Endoplasmic Reticulum: Smooth and Rough
15:08
Golgi Apparatus
17:55
Vacuole
20:43
Lysosome
22:01
Mitochondria
25:40
Peroxisomes
28:18
Cytoskeleton
30:41
Cytoplasm and Cytosol
30:53
Microtubules: Centrioles, Spindel Fibers, Clagell, Cillia
32:06
Microfilaments
36:39
Intermediate Filaments and Kerotin
38:52
Eukaryotic Cells (Plant Cell Structure)
40:08
Plasma Membrane, Primary Cell Wall, and Secondary Cell Wall
40:30
Middle Lamella
43:21
Central Cauole
44:12
Plastids: Leucoplasts, Chromoplasts, Chrloroplasts
45:35
Chloroplasts
47:06
Example 1: Structures and Functions
48:46
Example 2: Cell Walls
51:19
Example 3: Cytoskeleton
52:53
Example 4: Antibiotics and the Endosymbiosis Theory
56:55
Cell Membranes and Transport

53m 10s

Intro
0:00
Cell Membrane Structure
0:09
Phospholipids Bilayer
0:11
Chemical Structure: Amphipathic and Fatty Acids
0:25
Cell Membrane Proteins
2:44
Fluid Mosaic Model
2:45
Peripheral Proteins and Integral Proteins
3:19
Transmembrane Proteins
4:34
Cholesterol
4:48
Functions of Membrane Proteins
6:39
Transport Across Cell Membranes
9:52
Transport Across Cell Membranes
9:53
Methods of Passive Transport
12:07
Passive and Active Transport
12:08
Simple Diffusion
12:45
Facilitated Diffusion
15:20
Osmosis
17:17
Definition and Example of Osmosis
17:18
Hypertonic, Hypotonic, and Isotonic
21:47
Active Transport
27:57
Active Transport
28:17
Sodium and Potassium Pump
29:45
Cotransport
34:38
2 Types of Active Transport
37:09
Endocytosis and Exocytosis
37:38
Endocytosis and Exocytosis
37:51
Types of Endocytosis: Pinocytosis
40:39
Types of Endocytosis: Phagocytosis
41:02
Receptor Mediated Endocytosis
41:27
Receptor Mediated Endocytosis
41:28
Example 1: Cell Membrane and Permeable Substances
43:59
Example 2: Osmosis
45:20
Example 3: Active Transport, Cotransport, Simple and Facilitated Diffusion
47:36
Example 4: Match Terms with Definition
50:55
Cellular Communication

57m 9s

Intro
0:00
Extracellular Matrix
0:28
The Extracellular Matrix (ECM)
0:29
ECM in Animal Cells
0:55
Fibronectin and Integrins
1:34
Intercellular Communication in Plants
2:48
Intercellular Communication in Plants: Plasmodesmata
2:50
Cell to Cell Communication in Animal Cells
3:39
Cell Junctions
3:42
Desmosomes
3:54
Tight Junctions
5:07
Gap Junctions
7:00
Cell Signaling
8:17
Cell Signaling: Ligand and Signal Transduction Pathway
8:18
Direct Contact
8:48
Over Distances Contact and Hormones
10:09
Stages of Cell Signaling
11:53
Reception Phase
11:54
Transduction Phase
13:49
Response Phase
14:45
Cell Membrane Receptors
15:37
G-Protein Coupled Receptor
15:38
Cell Membrane Receptor, Cont.
21:37
Receptor Tyrosine Kinases (RTKs)
21:38
Autophosphorylation, Monomer, and Dimer
22:57
Cell Membrane Receptor, Cont.
27:01
Ligand-Gated Ion Channels
27:02
Intracellular Receptors
29:43
Intracellular Receptor and Receptor -Ligand Complex
29:44
Signal Transduction
32:57
Signal Transduction Pathways
32:58
Adenylyl Cyclase and cAMP
35:53
Second Messengers
39:18
cGMP, Inositol Trisphosphate, and Diacylglycerol
39:20
Cell Response
45:15
Cell Response
45:16
Apoptosis
46:57
Example 1: Tight Junction and Gap Junction
48:29
Example 2: Three Phases of Cell Signaling
51:48
Example 3: Ligands and Binding of Hormone
54:03
Example 4: Signal Transduction
56:06
Section 3: Cell Division
The Cell Cycle

37m 49s

Intro
0:00
Functions of Cell Division
0:09
Overview of Cell Division: Reproduction, Growth, and Repair
0:11
Important Term: Daughter Cells
2:25
Chromosome Structure
3:36
Chromosome Structure: Sister Chromatids and Centromere
3:37
Chromosome Structure: Chromatin
4:31
Chromosome with One Chromatid or Two Chromatids
5:25
Chromosome Structure: Long and Short Arm
6:49
Mitosis and Meiosis
7:00
Mitosis
7:41
Meiosis
8:40
The Cell Cycle
10:43
Mitotic Phase and Interphase
10:44
Cytokinesis
15:51
Cytokinesis in Animal Cell: Cleavage Furrow
15:52
Cytokinesis in Plant Cell: Cell Plate
17:28
Control of the Cell Cycle
18:28
Cell Cycle Control System and Checkpoints
18:29
Cyclins and Cyclin Dependent Kinases
21:18
Cyclins and Cyclin Dependent Kinases (CDKSs)
21:20
MPF
23:17
Internal Factor Regulating Cell Cycle
24:00
External Factor Regulating Cell Cycle
24:53
Contact Inhibition and Anchorage Dependent
25:53
Cancer and the Cell Cycle
27:42
Cancer Cells
27:46
Example1: Parts of the Chromosome
30:15
Example 2: Cell Cycle
31:50
Example 3: Control of the Cell Cycle
33:32
Example 4: Cancer and the Cell
35:01
Mitosis

35m 1s

Intro
0:00
Review of the Cell Cycle
0:09
Interphase: G1 Phase
0:34
Interphase: S Phase
0:56
Interphase: G2 Phase
1:31
M Phase: Mitosis and Cytokinesis
1:47
Overview of Mitosis
3:08
What is Mitosis?
3:10
Overview of Mitosis
3:17
Diploid and Haploid
5:37
Homologous Chromosomes
6:04
The Spindle Apparatus
11:57
The Spindle Apparatus
12:00
Centrosomes and Centrioles
12:40
Microtubule Organizing Center
13:03
Spindle Fiber of Spindle Microtubules
13:23
Kinetochores
14:06
Asters
15:45
Prophase
16:47
First Phase of Mitosis: Prophase
16:54
Metaphase
20:05
Second Phase of Mitosis: Metaphase
20:10
Anaphase
22:52
Third Phase of Mitosis: Anaphase
22:53
Telophase and Cytokinesis
24:34
Last Phase of Mitosis: Telophase and Cytokinesis
24:35
Summary of Mitosis
27:46
Summary of Mitosis
27:47
Example 1: Spindle Apparatus
28:50
Example 2: Last Phase of Mitosis
30:39
Example 3: Prophase
32:41
Example 4: Identify the Phase
33:52
Meiosis

1h 58s

Intro
0:00
Haploid and Diploid Cells
0:09
Diploid and Somatic Cells
0:29
Haploid and Gametes
1:20
Example: Human Cells and Chromosomes
1:41
Sex Chromosomes
6:00
Comparison of Mitosis and Meiosis
10:42
Mitosis Vs. Meiosis: Cell Division
10:59
Mitosis Vs. Meiosis: Daughter Cells
12:31
Meiosis: Pairing of Homologous Chromosomes
13:40
Mitosis and Meiosis
14:21
Process of Mitosis
14:27
Process of Meiosis
16:12
Synapsis and Crossing Over
19:14
Prophase I: Synapsis and Crossing Over
19:15
Chiasmata
22:33
Meiosis I
25:49
Prophase I: Crossing Over
25:50
Metaphase I: Homologs Line Up
26:00
Anaphase I: Homologs Separate
28:16
Telophase I and Cytokinesis
29:15
Independent Assortment
30:58
Meiosis II
32:17
Propphase II
33:50
Metaphase II
34:06
Anaphase II
34:50
Telophase II
36:09
Cytokinesis
37:00
Summary of Meiosis
38:15
Summary of Meiosis
38:16
Cell Division Mechanism in Plants
41:57
Example 1: Cell Division and Meiosis
46:15
Example 2: Phases of Meiosis
50:22
Example 3: Label the Figure
54:29
Example 4: Four Differences Between Mitosis and Meiosis
56:37
Section 4: Cellular Energetics
Enzymes

51m 3s

Intro
0:00
Law of Thermodynamics
0:08
Thermodynamics
0:09
The First Law of Thermodynamics
0:37
The Second Law of Thermodynamics
1:24
Entropy
1:35
The Gibbs Free Energy Equation
3:07
The Gibbs Free Energy Equation
3:08
ATP
8:23
Adenosine Triphosphate (ATP)
8:24
Cellular Respiration
11:32
Catabolic Pathways
12:28
Anabolic Pathways
12:54
Enzymes
14:31
Enzymes
14:32
Enzymes and Exergonic Reaction
14:40
Enzymes and Endergonic Reaction
16:36
Enzyme Specificity
21:29
Substrate
21:41
Induced Fit
23:04
Factors Affecting Enzyme Activity
25:55
Substrate Concentration
26:07
pH
27:10
Temperature
29:14
Presence of Cofactors
29:57
Regulation of Enzyme Activity
31:12
Competitive Inhibitors
32:13
Noncompetitive Inhibitors
33:52
Feedback Inhibition
35:22
Allosteric Interactions
36:56
Allosteric Regulators
37:00
Example 1: Is the Inhibitor Competitive or Noncompetitive?
40:49
Example 2: Thermophiles
44:18
Example 3: Exergonic or Endergonic
46:09
Example 4: Energy Vs. Reaction Progress Graph
48:47
Glycolysis and Anaerobic Respiration

38m 1s

Intro
0:00
Cellular Respiration Overview
0:13
Cellular Respiration
0:14
Anaerobic Respiration vs. Aerobic Respiration
3:50
Glycolysis Overview
4:48
Overview of Glycolysis
4:50
Glycolysis Involves a Redox Reaction
7:02
Redox Reaction
7:04
Glycolysis
15:04
Important Facts About Glycolysis
15:07
Energy Invested Phase
16:12
Splitting of Fructose 1,6-Phosphate and Energy Payoff Phase
17:50
Substrate Level Phophorylation
22:12
Aerobic Versus Anaerobic Respiration
23:57
Aerobic Versus Anaerobic Respiration
23:58
Cellular Respiration Overview
27:15
When Cellular Respiration is Anaerobic
27:17
Glycolysis
28:26
Alcohol Fermentation
28:45
Lactic Acid Fermentation
29:58
Example 1: Glycolysis
31:04
Example 2: Glycolysis, Fermentation and Anaerobic Respiration
33:44
Example 3: Aerobic Respiration Vs. Anaerobic Respiration
35:25
Example 4: Exergonic Reaction and Endergonic Reaction
36:42
Aerobic Respiration

51m 6s

Intro
0:00
Aerobic Vs. Anaerobic Respiration
0:06
Aerobic and Anaerobic Comparison
0:07
Review of Glycolysis
1:48
Overview of Glycolysis
2:06
Glycolysis: Energy Investment Phase
2:25
Glycolysis: Energy Payoff Phase
2:58
Conversion of Pyruvate to Acetyl CoA
4:55
Conversion of Pyruvate to Acetyl CoA
4:56
Energy Formation
8:06
Mitochondrial Structure
8:58
Endosymbiosis Theory
9:23
Matrix
10:00
Outer Membrane, Inner Membrane, and Intermembrane Space
10:43
Cristae
11:47
The Citric Acid Cycle
12:11
The Citric Acid Cycle (Also Called Krebs Cycle)
12:12
Substrate Level Phosphorylation
18:47
Summary of ATP, NADH, and FADH2 Production
23:13
Process: Glycolysis
23:28
Process: Acetyl CoA Production
23:36
Process: Citric Acid Cycle
23:52
The Electron Transport Chain
24:24
Oxidative Phosphorylation
24:28
The Electron Transport Chain and ATP Synthase
25:20
Carrier Molecules: Cytochromes
27:18
Carrier Molecules: Flavin Mononucleotide (FMN)
28:05
Chemiosmosis
32:46
The Process of Chemiosmosis
32:47
Summary of ATP Produced by Aerobic Respiration
38:24
ATP Produced by Aerobic Respiration
38:27
Example 1: Aerobic Respiration
43:38
Example 2: Label the Location for Each Process and Structure
45:08
Example 3: The Electron Transport Chain
47:06
Example 4: Mitochondrial Inner Membrane
48:38
Photosynthesis

1h 2m 52s

Intro
0:00
Photosynthesis
0:09
Introduction to Photosynthesis
0:10
Autotrophs and Heterotrophs
0:25
Overview of Photosynthesis Reaction
1:05
Leaf Anatomy and Chloroplast Structure
2:54
Chloroplast
2:55
Cuticle
3:16
Upper Epidermis
3:27
Mesophyll
3:40
Stomates
4:00
Guard Cells
4:45
Transpiration
5:01
Vascular Bundle
5:20
Stroma and Double Membrane
6:20
Grana
7:17
Thylakoids
7:30
Dark Reaction and Light Reaction
7:46
Light Reactions
8:43
Light Reactions
8:47
Pigments: Chlorophyll a, Chlorophyll b, and Carotenoids
9:19
Wave and Particle
12:10
Photon
12:34
Photosystems
13:24
Photosystems
13:28
Reaction-Center Complex and Light Harvesting Complexes
14:01
Noncyclic Photophosphorylation
17:46
Noncyclic Photophosphorylation Overview
17:47
What is Photophosphorylation?
18:25
Noncyclic Photophosphorylation Process
19:07
Photolysis and The Rest of Noncyclic Photophosphorylation
21:33
Cyclic Photophosphorylation
31:45
Cyclic Photophosphorylation
31:46
Light Independent Reactions
34:34
The Calvin Cycle
34:35
C3 Plants and Photorespiration
40:31
C3 Plants and Photorespiration
40:32
C4 Plants
45:32
C4 Plants: Structures and Functions
45:33
CAM Plants
50:25
CAM Plants: Structures and Functions
50:35
Example 1: Calvin Cycle
54:34
Example 2: C4 Plant
55:48
Example 3: Photosynthesis and Photorespiration
58:35
Example 4: CAM Plants
1:00:41
Section 5: Molecular Genetics
DNA Synthesis

38m 45s

Intro
0:00
Review of DNA Structure
0:09
DNA Molecules
0:10
Nitrogenous Base: Pyrimidines and Purines
1:25
DNA Double Helix
3:03
Complementary Strands of DNA
3:12
5' to 3' & Antiparallel
4:55
Overview of DNA Replication
7:10
DNA Replication & Semiconservative
7:11
DNA Replication
10:26
Origin of Replication
10:28
Helicase
11:10
Single-Strand Binding Protein
12:05
Topoisomerases
13:14
DNA Polymerase
14:26
Primase
15:55
Leading and Lagging Strands
16:51
Leading Strand and Lagging Strand
16:52
Okazaki Fragments
18:10
DNA Polymerase I
20:11
Ligase
21:12
Proofreading and Mismatch Repair
22:18
Proofreading
22:19
Mismatch
23:33
Telomeres
24:58
Telomeres
24:59
Example 1: Function of Enzymes During DNA Synthesis
28:09
Example 2: Accuracy of the DNA Sequence
31:42
Example 3: Leading Strand and Lagging Strand
32:38
Example 4: Telomeres
35:40
Transcription and Translation

1h 17m 1s

Intro
0:00
Transcription and Translation Overview
0:07
From DNA to RNA to Protein
0:09
Structure and Types of RNA
3:14
Structure and Types of RNA
3:33
mRNA
6:19
rRNA
7:02
tRNA
7:28
Transcription
7:54
Initiation Phase
8:11
Elongation Phase
12:12
Termination Phase
14:51
RNA Processing
16:11
Types of RNA Processing
16:12
Exons and Introns
16:35
Splicing & Spliceosomes
18:27
Addition of a 5' Cap and a Poly A tail
20:41
Alternative Splicing
21:43
Translation
23:41
Nucleotide Triplets or Codons
23:42
Start Codon
25:24
Stop Codons
25:38
Coding of Amino Acids and Wobble Position
25:57
Translation Cont.
28:29
Transfer RNA (tRNA): Structures and Functions
28:30
Ribosomes
35:15
Peptidyl, Aminoacyl, and Exit Site
35:23
Steps of Translation
36:58
Initiation Phase
37:12
Elongation Phase
43:12
Termination Phase
45:28
Mutations
49:43
Types of Mutations
49:44
Substitutions: Silent
51:11
Substitutions: Missense
55:27
Substitutions: Nonsense
59:37
Insertions and Deletions
1:01:10
Example 1: Three Types of Processing that are Performed on pre-mRNA
1:06:53
Example 2: The Process of Translation
1:09:10
Example 3: Transcription
1:12:04
Example 4: Three Types of Substitution Mutations
1:14:09
Viral Structure and Genetics

43m 12s

Intro
0:00
Structure of Viruses
0:09
Structure of Viruses: Capsid and Envelope
0:10
Bacteriophage
1:48
Other Viruses
2:28
Overview of Viral Reproduction
3:15
Host Range
3:48
Step 1: Bind to Host Cell
4:39
Step 2: Viral Nuclei Acids Enter the Cell
5:15
Step 3: Viral Nucleic Acids & Proteins are Synthesized
5:54
Step 4: Virus Assembles
6:34
Step 5: Virus Exits the Cell
6:55
The Lytic Cycle
7:37
Steps in the Lytic Cycle
7:38
The Lysogenic Cycle
11:27
Temperate Phage
11:34
Steps in the Lysogenic Cycle
12:09
RNA Viruses
16:57
Types of RNA Viruses
17:15
Positive Sense
18:16
Negative Sense
18:48
Reproductive Cycle of RNA Viruses
19:32
Retroviruses
25:48
Complementary DNA (cDNA) & Reverse Transcriptase
25:49
Life Cycle of a Retrovirus
28:22
Prions
32:42
Prions: Definition and Examples
32:45
Viroids
34:46
Example 1: The Lytic Cycle
35:37
Example 2: Retrovirus
38:03
Example 3: Positive Sense RNA vs. Negative Sense RNA
39:10
Example 4: The Lysogenic Cycle
40:42
Bacterial Genetics and Gene Regulation

49m 45s

Intro
0:00
Bacterial Genomes
0:09
Structure of Bacterial Genomes
0:16
Transformation
1:22
Transformation
1:23
Vector
2:49
Transduction
3:32
Process of Transduction
3:38
Conjugation
8:06
Conjugation & F factor
8:07
Operons
14:02
Definition and Example of Operon
14:52
Structural Genes
16:23
Promoter Region
17:04
Regulatory Protein & Operators
17:53
The lac Operon
20:09
The lac Operon: Inducible System
20:10
The trp Operon
28:02
The trp Operon: Repressible System
28:03
Corepressor
31:37
Anabolic & Catabolic
33:12
Positive Regulation of the lac Operon
34:39
Positive Regulation of the lac Operon
34:40
Example 1: The Process of Transformation
39:07
Example 2: Operon & Terms
43:29
Example 3: Inducible lac Operon and Repressible trp Operon
45:15
Example 4: lac Operon
47:10
Eukaryotic Gene Regulation and Mobile Genetic Elements

54m 26s

Intro
0:00
Mechanism of Gene Regulation
0:11
Differential Gene Expression
0:13
Levels of Regulation
2:24
Chromatin Structure and Modification
4:35
Chromatin Structure
4:36
Levels of Packing
5:50
Euchromatin and Heterochromatin
8:58
Modification of Chromatin Structure
9:58
Epigenetic
12:49
Regulation of Transcription
14:20
Promoter Region, Exon, and Intron
14:26
Enhancers: Control Element
15:31
Enhancer & DNA-Bending Protein
17:25
Coordinate Control
21:23
Silencers
23:01
Post-Transcriptional Regulation
24:05
Post-Transcriptional Regulation
24:07
Alternative Splicing
27:19
Differences in mRNA Stability
28:02
Non-Coding RNA Molecules: micro RNA & siRNA
30:01
Regulation of Translation and Post-Translational Modifications
32:31
Regulation of Translation and Post-Translational Modifications
32:55
Ubiquitin
35:21
Proteosomes
36:04
Transposons
37:50
Mobile Genetic Elements
37:56
Barbara McClintock
38:37
Transposons & Retrotransposons
40:38
Insertion Sequences
43:14
Complex Transposons
43:58
Example 1: Four Mechanisms that Decrease Production of Protein
45:13
Example 2: Enhancers and Gene Expression
49:09
Example 3: Primary Transcript
50:41
Example 4: Retroviruses and Retrotransposons
52:11
Biotechnology

49m 26s

Intro
0:00
Definition of Biotechnology
0:08
Biotechnology
0:09
Genetic Engineering
1:05
Example: Golden Corn
1:57
Recombinant DNA
2:41
Recombinant DNA
2:42
Transformation
3:24
Transduction
4:24
Restriction Enzymes, Restriction Sites, & DNA Ligase
5:32
Gene Cloning
13:48
Plasmids
14:20
Gene Cloning: Step 1
17:35
Gene Cloning: Step 2
17:57
Gene Cloning: Step 3
18:53
Gene Cloning: Step 4
19:46
Gel Electrophoresis
27:25
What is Gel Electrophoresis?
27:26
Gel Electrophoresis: Step 1
28:13
Gel Electrophoresis: Step 2
28:24
Gel Electrophoresis: Step 3 & 4
28:39
Gel Electrophoresis: Step 5
29:55
Southern Blotting
31:25
Polymerase Chain Reaction (PCR)
32:11
Polymerase Chain Reaction (PCR)
32:12
Denaturing Phase
35:40
Annealing Phase
36:07
Elongation/ Extension Phase
37:06
DNA Sequencing and the Human Genome Project
39:19
DNA Sequencing and the Human Genome Project
39:20
Example 1: Gene Cloning
40:40
Example 2: Recombinant DNA
43:04
Example 3: Match Terms With Descriptions
45:43
Example 4: Polymerase Chain Reaction
47:36
Section 6: Heredity
Mendelian Genetics

1h 32m 8s

Intro
0:00
Background
0:40
Gregory Mendel & Mendel's Law
0:41
Blending Hypothesis
1:04
Particulate Inheritance
2:08
Terminology
2:55
Gene
3:05
Locus
3:57
Allele
4:37
Dominant Allele
5:48
Recessive Allele
7:38
Genotype
9:22
Phenotype
10:01
Homozygous
10:44
Heterozygous
11:39
Penetrance
11:57
Expressivity
14:15
Mendel's Experiments
15:31
Mendel's Experiments: Pea Plants
15:32
The Law of Segregation
21:16
Mendel's Conclusions
21:17
The Law of Segregation
22:57
Punnett Squares
28:27
Using Punnet Squares
28:30
The Law of Independent Assortment
32:35
Monohybrid
32:38
Dihybrid
33:29
The Law of Independent Assortment
34:00
The Law of Independent Assortment, cont.
38:13
The Law of Independent Assortment: Punnet Squares
38:29
Meiosis and Mendel's Laws
43:38
Meiosis and Mendel's Laws
43:39
Test Crosses
49:07
Test Crosses Example
49:08
Probability: Multiplication Rule and the Addition Rule
53:39
Probability Overview
53:40
Independent Events & Multiplication Rule
55:40
Mutually Exclusive Events & Addition Rule
1:00:25
Incomplete Dominance, Codominance and Multiple Alleles
1:02:55
Incomplete Dominance
1:02:56
Incomplete Dominance, Codominance and Multiple Alleles
1:07:06
Codominance and Multiple Alleles
1:07:08
Polygenic Inheritance and Pleoitropy
1:10:19
Polygenic Inheritance and Pleoitropy
1:10:26
Epistasis
1:12:51
Example of Epistasis
1:12:52
Example 1: Genetic of Eye Color and Height
1:17:39
Example 2: Blood Type
1:21:57
Example 3: Pea Plants
1:25:09
Example 4: Coat Color
1:28:34
Linked Genes and Non-Mendelian Modes of Inheritance

39m 38s

Intro
0:00
Review of the Law of Independent Assortment
0:14
Review of the Law of Independent Assortment
0:24
Linked Genes
6:06
Linked Genes
6:07
Bateson & Pannett: Pea Plants
8:00
Crossing Over and Recombination
15:17
Crossing Over and Recombination
15:18
Extranuclear Genes
20:50
Extranuclear Genes
20:51
Cytoplasmic Genes
21:31
Genomic Imprinting
23:45
Genomic Imprinting
23:58
Methylation
24:43
Example 1: Recombination Frequencies & Linkage Map
27:07
Example 2: Linked Genes
28:39
Example 3: Match Terms to Correct Descriptions
36:46
Example 4: Leber's Optic Neuropathy
38:40
Sex-Linked Traits and Pedigree Analysis

43m 39s

Intro
0:00
Sex-Linked Traits
0:09
Human Chromosomes, XY, and XX
0:10
Thomas Morgan's Drosophila
1:44
X-Inactivation and Barr Bodies
14:48
X-Inactivation Overview
14:49
Calico Cats Example
17:04
Pedigrees
19:24
Definition and Example of Pedigree
19:25
Autosomal Dominant Inheritance
20:51
Example: Huntington's Disease
20:52
Autosomal Recessive Inheritance
23:04
Example: Cystic Fibrosis, Tay-Sachs Disease, and Phenylketonuria
23:05
X-Linked Recessive Inheritance
27:06
Example: Hemophilia, Duchene Muscular Dystrohpy, and Color Blindess
27:07
Example 1: Colorblind
29:48
Example 2: Pedigree
37:07
Example 3: Inheritance Pattern
39:54
Example 4: X-inactivation
41:17
Section 7: Evolution
Natural Selection

1h 3m 28s

Intro
0:00
Background
0:09
Work of Other Scientists
0:15
Aristotle
0:43
Carl Linnaeus
1:32
George Cuvier
2:47
James Hutton
4:10
Thomas Malthus
5:05
Jean-Baptiste Lamark
5:45
Darwin's Theory of Natural Selection
7:50
Evolution
8:00
Natural Selection
8:43
Charles Darwin & The Galapagos Islands
10:20
Genetic Variation
20:37
Mutations
20:38
Independent Assortment
21:04
Crossing Over
24:40
Random Fertilization
25:26
Natural Selection and the Peppered Moth
26:37
Natural Selection and the Peppered Moth
26:38
Types of Natural Selection
29:52
Directional Selection
29:55
Stabilizing Selection
32:43
Disruptive Selection
34:21
Sexual Selection
36:18
Sexual Dimorphism
37:30
Intersexual Selection
37:57
Intrasexual Selection
39:20
Evidence for Evolution
40:55
Paleontology: Fossil Record
41:30
Biogeography
45:35
Continental Drift
46:06
Pangaea
46:28
Marsupials
47:11
Homologous and Analogous Structure
50:10
Homologous Structure
50:12
Analogous Structure
53:21
Example 1: Genetic Variation & Natural Selection
56:15
Example 2: Types of Natural Selection
58:07
Example 3: Mechanisms By Which Genetic Variation is Maintained Within a Population
1:00:12
Example 4: Difference Between Homologous and Analogous Structures
1:01:28
Population Genetic and Evolution

53m 22s

Intro
0:00
Review of Natural Selection
0:12
Review of Natural Selection
0:13
Genetic Drift and Gene Flow
4:40
Definition of Genetic Drift
4:41
Example of Genetic Drift: Cholera Epidemic
5:15
Genetic Drift: Founder Effect
7:28
Genetic Drift: Bottleneck Effect
10:27
Gene Flow
13:00
Quantifying Genetic Variation
14:32
Average Heterozygosity
15:08
Nucleotide Variation
17:05
Maintaining Genetic Variation
18:12
Heterozygote Advantage
19:45
Example of Heterozygote Advantage: Sickle Cell Anemia
20:21
Diploidy
23:44
Geographic Variation
26:54
Frequency Dependent Selection and Outbreeding
28:15
Neutral Traits
30:55
The Hardy-Weinberg Equilibrium
31:11
The Hardy-Weinberg Equilibrium
31:49
The Hardy-Weinberg Conditions
32:42
The Hardy-Weinberg Equation
34:05
The Hardy-Weinberg Example
36:33
Example 1: Match Terms to Descriptions
42:28
Example 2: The Hardy-Weinberg Equilibrium
44:31
Example 3: The Hardy-Weinberg Equilibrium
49:10
Example 4: Maintaining Genetic Variation
51:30
Speciation and Patterns of Evolution

51m 2s

Intro
0:00
Early Life on Earth
0:08
Early Earth
0:09
1920's Oparin & Haldane
0:58
Abiogenesis
2:15
1950's Miller & Urey
2:45
Ribozymes
5:34
3.5 Billion Years Ago
6:39
2.5 Billion Years Ago
7:14
1.5 Billion Years Ago
7:41
Endosymbiosis
8:00
540 Million Years Ago: Cambrian Explosion
9:57
Gradualism and Punctuated Equilibrium
11:46
Gradualism
11:47
Punctuated Equilibrium
12:45
Adaptive Radiation
15:08
Adaptive Radiation
15:09
Example of Adaptive Radiation: Galapogos Islands
17:11
Convergent Evolution, Divergent Evolution, and Coevolution
18:30
Convergent Evolution
18:39
Divergent Evolution
21:30
Coevolution
23:49
Speciation
26:27
Definition and Example of Species
26:29
Reproductive Isolation: Prezygotive
27:49
Reproductive Isolation: Post zygotic
29:28
Allopatric Speciation
30:21
Allopatric Speciation & Geographic Isolation
30:28
Genetic Drift
31:31
Sympatric Speciation
34:10
Sympatric Speciation
34:11
Polyploidy & Autopolyploidy
35:12
Habitat Isolation
39:17
Temporal Isolation
41:27
Selection Selection
41:40
Example 1: Pattern of Evolution
42:53
Example 2: Sympatric Speciation
45:16
Example 3: Patterns of Evolution
48:08
Example 4: Patterns of Evolution
49:27
Section 8: Diversity of Life
Classification

1h 51s

Intro
0:00
Systems of Classification
0:07
Taxonomy
0:08
Phylogeny
1:04
Phylogenetics Tree
1:44
Cladistics
3:37
Classification of Organisms
5:31
Example of Carl Linnaeus System
5:32
Domains
9:26
Kingdoms: Monera, Protista, Plantae, Fungi, Animalia
9:27
Monera
10:06
Phylogentics Tree: Eurkarya, Bacteria, Archaea
11:58
Domain Eukarya
12:50
Domain Bacteria
15:43
Domain Bacteria
15:46
Pathogens
16:41
Decomposers
18:00
Domain Archaea
19:43
Extremophiles Archaea: Thermophiles and Halophiles
19:44
Methanogens
20:58
Phototrophs, Autotrophs, Chemotrophs and Heterotrophs
24:40
Phototrophs and Chemotrophs
25:02
Autotrophs and Heterotrophs
26:54
Photoautotrophs
28:50
Photoheterotrophs
29:28
Chemoautotrophs
30:06
Chemoheterotrophs
31:37
Domain Eukarya
32:40
Domain Eukarya
32:43
Plant Kingdom
34:28
Protists
35:48
Fungi Kingdom
37:06
Animal Kingdom
38:35
Body Symmetry
39:25
Lack Symetry
39:40
Radial Symmetry: Sea Aneome
40:15
Bilateral Symmetry
41:55
Cephalization
43:29
Germ Layers
44:54
Diploblastic Animals
45:18
Triploblastic Animals
45:25
Ectoderm
45:36
Endoderm
46:07
Mesoderm
46:41
Coelomates
47:14
Coelom
47:15
Acoelomate
48:22
Pseudocoelomate
48:59
Coelomate
49:31
Protosomes
50:46
Deuterosomes
51:20
Example 1: Domains
53:01
Example 2: Match Terms with Descriptions
56:00
Example 3: Kingdom Monera and Domain Archaea
57:50
Example 4: System of Classification
59:37
Bacteria

36m 46s

Intro
0:00
Comparison of Domain Archaea and Domain Bacteria
0:08
Overview of Archaea and Bacteria
0:09
Archaea vs. Bacteria: Nucleus, Organelles, and Organization of Genetic Material
1:45
Archaea vs. Bacteria: Cell Walls
2:20
Archaea vs. Bacteria: Number of Types of RNA Pol
2:29
Archaea vs. Bacteria: Membrane Lipids
2:53
Archaea vs. Bacteria: Introns
3:33
Bacteria: Pathogen
4:03
Bacteria: Decomposers and Fix Nitrogen
5:18
Bacteria: Aerobic, Anaerobic, Strict Anaerobes & Facultative Anaerobes
6:02
Phototrophs, Autotrophs, Heterotrophs and Chemotrophs
7:14
Phototrophs and Chemotrophs
7:50
Autotrophs and Heterotrophs
8:53
Photoautotrophs and Photoheterotrophs
10:15
Chemoautotroph and Chemoheterotrophs
11:07
Structure of Bacteria
12:21
Shapes: Cocci, Bacilli, Vibrio, and Spirochetes
12:26
Structures: Plasma Membrane and Cell Wall
14:23
Structures: Nucleoid Region, Plasmid, and Capsule Basal Apparatus, and Filament
15:30
Structures: Flagella, Basal Apparatus, Hook, and Filament
16:36
Structures: Pili, Fimbrae and Ribosome
18:00
Peptidoglycan: Gram + and Gram -
18:50
Bacterial Genomes and Reproduction
21:14
Bacterial Genomes
21:21
Reproduction of Bacteria
22:13
Transformation
23:26
Vector
24:34
Competent
25:15
Conjugation
25:53
Conjugation: F+ and R Plasmids
25:55
Example 1: Species
29:41
Example 2: Bacteria and Exchange of Genetic Material
32:31
Example 3: Ways in Which Bacteria are Beneficial to Other Organisms
33:48
Example 4: Domain Bacteria vs. Domain Archaea
34:53
Protists

1h 18m 48s

Intro
0:00
Classification of Protists
0:08
Classification of Protists
0:09
'Plant-like' Protists
2:06
'Animal-like' Protists
3:19
'Fungus-like' Protists
3:57
Serial Endosymbiosis Theory
5:15
Endosymbiosis Theory
5:33
Photosynthetic Protists
7:33
Life Cycles with a Diploid Adult
13:35
Life Cycles with a Diploid Adult
13:56
Life Cycles with a Haploid Adult
15:31
Life Cycles with a Haploid Adult
15:32
Alternation of Generations
17:22
Alternation of Generations: Multicellular Haploid & Diploid Phase
17:23
Plant-Like Protists
19:58
Euglenids
20:43
Dino Flagellates
22:57
Diatoms
26:07
Plant-Like Protists
28:44
Golden Algae
28:45
Brown Algeas
30:05
Plant-Like Protists
33:38
Red Algae
33:39
Green Algae
35:36
Green Algae: Chlamydomonus
37:44
Animal-Like Protists
40:04
Animal-Like Protists Overview
40:05
Sporozoans (Apicomplexans)
40:32
Alveolates
41:41
Sporozoans (Apicomplexans): Plasmodium & Malaria
42:59
Animal-Like Protists
48:44
Kinetoplastids
48:50
Example of Kinetoplastids: Trypanosomes & African Sleeping Sickness
49:30
Ciliate
50:42
Conjugation
53:16
Conjugation
53:26
Animal-Like Protists
57:08
Parabasilids
57:31
Diplomonads
59:06
Rhizopods
1:00:13
Forams
1:02:25
Radiolarians
1:03:28
Fungus-Like Protists
1:04:25
Fungus-Like Protists Overview
1:04:26
Slime Molds
1:05:15
Cellular Slime Molds: Feeding Stage
1:09:21
Oomycetes
1:11:15
Example 1: Alternation of Generations and Sexual Life Cycles
1:13:05
Example 2: Match Protists to Their Descriptions
1:14:12
Example 3: Three Structures that Protists Use for Motility
1:16:22
Example 4: Paramecium
1:17:04
Fungi

35m 24s

Intro
0:00
Introduction to Fungi
0:09
Introduction to Fungi
0:10
Mycologist
0:34
Examples of Fungi
0:45
Hyphae, Mycelia, Chitin, and Coencytic Fungi
2:26
Ancestral Protists
5:00
Role of Fungi in the Environment
5:35
Fungi as Decomposers
5:36
Mycorrrhiza
6:19
Lichen
8:52
Life Cycle of Fungi
11:32
Asexual Reproduction
11:33
Sexual Reproduction & Dikaryotic Cell
13:16
Chytridiomycota
18:12
Phylum Chytridiomycota
18:17
Zoospores
18:50
Zygomycota
19:07
Coenocytic & Zygomycota Life Cycle
19:08
Basidiomycota
24:27
Basidiomycota Overview
24:28
Basidiomycota Life Cycle
26:11
Ascomycota
28:00
Ascomycota Overview
28:01
Ascomycota Reproduction
28:50
Example 1: Fungi Fill in the Blank
31:02
Example 2: Name Two Roles Played by Fungi in the Environment
32:09
Example 3: Difference Between Diploid Cell and Dikaryon Cell
33:42
Example 4: Phylum of Fungi, Flagellated Spore, Coencytic
34:36
Invertebrates

1h 3m 3s

Intro
0:00
Porifera (Sponges)
0:33
Chordata
0:56
Porifera (Sponges): Sessile, Layers, Aceolomates, and Filter Feeders
1:24
Amoebocytes Cell
4:47
Choanocytes Cell
5:56
Sexual Reproduction
6:28
Cnidaria
8:05
Cnidaria Overview
8:06
Polyp & Medusa: Gastrovasular Cavity
8:29
Cnidocytes
9:42
Anthozoa
10:40
Cubozoa
11:23
Hydrozoa
11:53
Scyphoza
13:25
Platyhelminthes (Flatworms)
13:58
Flatworms: Tribloblastic, Bilateral Symmetry, and Cephalization
13:59
GI System
15:33
Excretory System
16:07
Nervous System
17:00
Turbellarians
17:36
Trematodes
18:42
Monageneans
21:32
Cestoda
21:55
Rotifera (Rotifers)
23:45
Rotifers: Digestive Tract, Pseudocoelem, and Stuctures
23:46
Reproduction: Parthenogenesis
25:33
Nematoda (Roundworms)
26:44
Nematoda (Roundworms)
26:45
Parasites: Pinworms & Hookworms
27:26
Annelida
28:36
Annelida Overview
28:37
Open Circulatory
29:21
Closed Circulatory
30:18
Nervous System
31:19
Excretory System
31:43
Oligochaete
32:07
Leeches
33:22
Polychaetes
34:42
Mollusca
35:26
Mollusca Features
35:27
Major Part 1: Visceral Mass
36:21
Major Part 2: Head-foot Region
36:49
Major Part 3: Mantle
37:13
Radula
37:49
Circulatory, Reproductive, Excretory, and Nervous System
38:14
Major Classes of Molluscs
39:12
Gastropoda
39:17
Polyplacophora
40:15
Bivales
40:41
Cephalopods
41:42
Arthropoda
43:35
Arthropoda Overview
43:36
Segmented Bodies
44:14
Exoskeleton
44:52
Jointed Appendages
45:28
Hemolyph, Excretory & Respiratory System
45:41
Myriapoda & Centipedes
47:15
Cheliceriforms
48:20
Crustcea
49:31
Herapoda
50:03
Echinodermata
52:59
Echinodermata
53:00
Watrer Vascular System
54:20
Selected Characteristics of Invertebrates
57:11
Selected Characteristics of Invertebrates
57:12
Example 1: Phylum Description
58:43
Example 2: Complex Animals
59:50
Example 3: Match Organisms to the Correct Phylum
1:01:03
Example 4: Phylum Arthropoda
1:02:01
Vertebrates

1h 7s

Intro
0:00
Phylum Chordata
0:06
Chordates Overview
0:07
Notochord and Dorsal Hollow Nerve Chord
1:24
Pharyngeal Clefts, Arches, and Post-anal Tail
3:41
Invertebrate Chordates
6:48
Lancelets
7:13
Tunicates
8:02
Hagfishes: Craniates
8:55
Vertebrate Chordates
10:41
Veterbrates Overview
10:42
Lampreys
11:00
Gnathostomes
12:20
Six Major Classes of Vertebrates
12:53
chondrichthyes
14:23
Chondrichthyes Overview
14:24
Ectothermic and Endothermic
14:42
Sharks: Lateral Line System, Neuromastsn, and Gills
15:27
Oviparous and Viviparous
17:23
Osteichthyes (Bony Fishes)
18:12
Osteichythes (Bony Fishes) Overview
18:13
Operculum
19:05
Swim Bladder
19:53
Ray-Finned Fishes
20:34
Lobe-Finned Fishes
20:58
Tetrapods
22:36
Tetrapods: Definition and Examples
22:37
Amphibians
23:53
Amphibians Overview
23:54
Order Urodela
25:51
Order Apoda
27:03
Order Anura
27:55
Reptiles
30:19
Reptiles Overview
30:20
Amniotes
30:37
Examples of Reptiles
32:46
Reptiles: Ectotherms, Gas Exchange, and Heart
33:40
Orders of Reptiles
34:17
Sphenodontia, Squamata, Testudines, and Crocodilia
34:21
Birds
36:09
Birds and Dinosaurs
36:18
Theropods
38:00
Birds: High Metabolism, Respiratory System, Lungs, and Heart
39:04
Birds: Endothermic, Bones, and Feathers
40:15
Mammals
42:33
Mammals Overview
42:35
Diaphragm and Heart
42:57
Diphydont
43:44
Synapsids
44:41
Monotremes
46:36
Monotremes
46:37
Marsupials
47:12
Marsupials: Definition and Examples
47:16
Convergent Evolution
48:09
Eutherians (Placental Mammals)
49:42
Placenta
49:43
Order Carnivora
50:48
Order Raodentia
51:00
Order Cetaceans
51:14
Primates
51:41
Primates Overview
51:42
Nails and Hands
51:58
Vision
52:51
Social Care for Young
53:28
Brain
53:43
Example 1: Distinguishing Characteristics of Chordates
54:33
Example 2: Match Description to Correct Term
55:56
Example 3: Bird's Anatomy
57:38
Example 4: Vertebrate Animal, Marine Environment, and Ectothermic
59:14
Section 9: Plants
Seedless Plants

34m 31s

Intro
0:00
Origin and Classification of Plants
0:06
Origin and Classification of Plants
0:07
Non-Vascular vs. Vascular Plants
1:29
Seedless Vascular & Seed Plants
2:28
Angiosperms & Gymnosperms
2:50
Alternation of Generations
3:54
Alternation of Generations
3:55
Bryophytes
7:58
Overview of Bryrophytes
7:59
Example: Moss Gametophyte
9:29
Example: Moss Sporophyte
9:50
Moss Life Cycle
10:12
Moss Life Cycle
10:13
Seedless Vascular Plants
13:23
Vascular Structures: Cell Walls, and Lignin
13:24
Homosporous
17:11
Heterosporous
17:48
Adaptations to Life on land
21:10
Adaptation 1: Cell Walls
21:38
Adaptation 2: Vascular Plants
21:59
Adaptation 3 : Xylem & Phloem
22:31
Adaptation 4: Seeds
23:07
Adaptation 5: Pollen
23:35
Adaptation 6: Stomata
24:45
Adaptation 7: Reduced Gametophyte Generation
25:32
Example 1: Bryophytes
26:39
Example 2: Sporangium, Lignin, Gametophyte, and Antheridium
28:34
Example 3: Adaptations to Life on Land
29:47
Example 4: Life Cycle of Plant
32:06
Plant Structure

1h 1m 21s

Intro
0:00
Plant Tissue
0:05
Dermal Tissue
0:15
Vascular Tissue
0:39
Ground Tissue
1:31
Cell Types in Plants
2:14
Parenchyma Cells
2:24
Collenchyma Cells
3:21
Sclerenchyma Cells
3:59
Xylem
5:04
Xylem: Tracheids and Vessel Elements
6:12
Gymnosperms vs. Angiosperms
7:53
Phloem
8:37
Phloem: Structures and Function
8:38
Sieve-Tube Elements
8:45
Companion Cells & Sieve Plates
9:11
Roots
10:08
Taproots & Fibrous
10:09
Aerial Roots & Prop Roots
11:41
Structures and Functions of Root: Dicot & Monocot
13:00
Pericyle
16:57
The Nitrogen Cylce
18:05
The Nitrogen Cycle
18:06
Mycorrhizae
24:20
Mycorrhizae
24:23
Ectomycorrhiza
26:03
Endomycorrhiza
26:25
Stems
26:53
Stems
26:54
Vascular Bundles of Monocots and Dicots
28:18
Leaves
29:48
Blade & Petiole
30:13
Upper Epidermis, Lower Epidermis & Cuticle
30:39
Ground Tissue, Palisade Mesophyll, Spongy Mesophyll
31:35
Stomata Pores
33:23
Guard Cells
34:15
Vascular Tissues: Vascular Bundles and Bundle Sheath
34:46
Stomata
36:12
Stomata & Gas Exchange
36:16
Guard Cells, Flaccid, and Turgid
36:43
Water Potential
38:03
Factors for Opening Stoma
40:35
Factors Causing Stoma to Close
42:44
Overview of Plant Growth
44:23
Overview of Plant Growth
44:24
Primary Plant Growth
46:19
Apical Meristems
46:25
Root Growth: Zone of Cell Division
46:44
Root Growth: Zone of Cell Elongation
47:35
Root Growth: Zone of Cell Differentiation
47:55
Stem Growth: Leaf Primodia
48:16
Secondary Plant Growth
48:48
Secondary Plant Growth Overview
48:59
Vascular Cambium: Secondary Xylem and Phloem
49:38
Cork Cambium: Periderm and Lenticels
51:10
Example 1: Leaf Structures
53:30
Example 2: List Three Types of Plant Tissue and their Major Functions
55:13
Example 3: What are Two Factors that Stimulate the Opening or Closing of Stomata?
56:58
Example 4: Plant Growth
59:18
Gymnosperms and Angiosperms

1h 1m 51s

Intro
0:00
Seed Plants
0:22
Sporopollenin
0:58
Heterosporous: Megasporangia
2:49
Heterosporous: Microsporangia
3:19
Gymnosperms
5:20
Gymnosperms
5:21
Gymnosperm Life Cycle
7:30
Gymnosperm Life Cycle
7:31
Flower Structure
15:15
Petal & Pollination
15:48
Sepal
16:52
Stamen: Anther, Filament
17:05
Pistill: Stigma, Style, Ovule, Ovary
17:55
Complete Flowers
20:14
Angiosperm Gametophyte Formation
20:47
Male Gametophyte: Microsporocytes, Microsporangia & Meiosis
20:57
Female Gametophyte: Megasporocytes & Meiosis
24:22
Double Fertilization
25:43
Double Fertilization: Pollen Tube and Endosperm
25:44
Angiosperm Life Cycle
29:43
Angiosperm Life Cycle
29:48
Seed Structure and Development
33:37
Seed Structure and Development
33:38
Pollen Dispersal
37:53
Abiotic
38:28
Biotic
39:30
Prevention of Self-Pollination
40:48
Mechanism 1
41:08
Mechanism 2: Dioecious
41:37
Mechanism 3
42:32
Self-Incompatibility
43:08
Gametophytic Self-Incompatibility
44:38
Sporophytic Self-Incompatibility
46:50
Asexual Reproduction
48:33
Asexual Reproduction & Vegetative Propagation
48:34
Graftiry
50:19
Monocots and Dicots
51:34
Monocots vs.Dicots
51:35
Example 1: Double Fertilization
54:43
Example 2: Mechanisms of Self-Fertilization
56:02
Example 3: Monocots vs. Dicots
58:11
Example 4: Flower Structures
1:00:11
Transport of Nutrients and Water in Plants

40m 30s

Intro
0:00
Review of Plant Cell Structure
0:14
Cell Wall, Plasma Membrane, Middle lamella, and Cytoplasm
0:15
Plasmodesmata, Chloroplasts, and Central Vacuole
3:24
Water Absorption by Plants
4:28
Root Hairs and Mycorrhizae
4:30
Osmosis and Water Potential
5:41
Apoplast and Symplast Pathways
10:01
Apoplast and Symplast Pathways
10:02
Xylem Structure
21:02
Tracheids and Vessel Elements
21:03
Bulk Flow
23:00
Transpiration
23:26
Cohesion
25:10
Adhesion
26:10
Phloem Structure
27:25
Pholem
27:26
Sieve-Tube Elements
27:48
Companion Cells
28:17
Translocation
28:42
Sugar Source and Sugar Sink Overview
28:43
Example of Sugar Sink
30:01
Example of Sugar Source
30:48
Example 1: Match the Following Terms to their Description
33:17
Example 2: Water Potential
34:58
Example 3: Bulk Flow
36:56
Example 4: Sugar Sink and Sugar Source
38:33
Plant Hormones and Tropisms

48m 10s

Intro
0:00
Plant Cell Signaling
0:17
Plant Cell Signaling Overview
0:18
Step 1: Reception
1:03
Step 2: Transduction
2:32
Step 3: Response
2:58
Second Messengers
3:52
Protein Kinases
4:42
Auxins
6:14
Auxins
6:18
Indoleacetic Acid (IAA)
7:23
Cytokinins and Gibberellins
11:10
Cytokinins: Apical Dominance & Delay of Aging
11:16
Gibberellins: 'Bolting'
13:51
Ethylene
15:33
Ethylene
15:34
Positive Feedback
15:46
Leaf Abscission
18:05
Mechanical Stress: Triple Response
19:36
Abscisic Acid
21:10
Abscisic Acid
21:15
Tropisms
23:11
Positive Tropism
23:50
Negative Tropism
24:07
Statoliths
26:21
Phytochromes and Photoperiodism
27:48
Phytochromes: PR and PFR
27:56
Circadian Rhythms
32:06
Photoperiod
33:13
Photoperiodism
33:38
Gerner & Allard
34:35
Short-Day Plant
35:22
Long-Day Plant
37:00
Example 1: Plant Hormones
41:28
Example 2: Cytokinins & Gibberellins
43:00
Example 3: Match the Following Terms to their Description
44:46
Example 4: Hormones & Cell Response
46:14
Section 10: Animal Structure and Physiology
The Respiratory System

48m 14s

Intro
0:00
Gas Exchange in Animals
0:17
Respiration
0:19
Ventilation
1:09
Characteristics of Respiratory Surfaces
1:53
Gas Exchange in Aquatic Animals
3:05
Simple Aquatic Animals
3:06
Gills & Gas Exchange in Complex Aquatic Animals
3:49
Countercurrent Exchange
6:12
Gas Exchange in Terrestrial Animals
13:46
Earthworms
14:07
Internal Respiratory
15:35
Insects
16:55
Circulatory Fluid
19:06
The Human Respiratory System
21:21
Nasal Cavity, Pharynx, Larynx, and Epiglottis
21:50
Bronchus, Bronchiole, Trachea, and Alveoli
23:38
Pulmonary Surfactants
28:05
Circulatory System: Hemoglobin
29:13
Ventilation
30:28
Inspiration/Expiration: Diaphragm, Thorax, and Abdomen
30:33
Breathing Control Center: Regulation of pH
34:34
Example 1: Tracheal System in Insects
39:08
Example 2: Countercurrent Exchange
42:09
Example 3: Respiratory System
44:10
Example 4: Diaphragm, Ventilation, pH, and Regulation of Breathing
45:31
The Circulatory System

1h 20m 21s

Intro
0:00
Types of Circulatory Systems
0:07
Circulatory System Overview
0:08
Open Circulatory System
3:19
Closed Circulatory System
5:58
Blood Vessels
7:51
Arteries
8:16
Veins
10:01
Capillaries
12:35
Vasoconstriction and Vasodilation
13:10
Vasoconstriction
13:11
Vasodilation
13:47
Thermoregulation
14:32
Blood
15:53
Plasma
15:54
Cellular Component: Red Blood Cells
17:41
Cellular Component: White Blood Cells
20:18
Platelets
21:14
Blood Types
21:35
Clotting
27:04
Blood, Fibrin, and Clotting
27:05
Hemophilia
30:26
The Heart
31:09
Structures and Functions of the Heart
31:19
Pulmonary and Systemic Circulation
40:20
Double Circuit: Pulmonary Circuit and Systemic Circuit
40:21
The Cardiac Cycle
42:35
The Cardiac Cycle
42:36
Autonomic Nervous System
50:00
Hemoglobin
51:25
Hemoglobin & Hemocyanin
51:26
Oxygen-Hemoglobin Dissociation Curve
55:30
Oxygen-Hemoglobin Dissociation Curve
55:44
Transport of Carbon Dioxide
1:06:31
Transport of Carbon Dioxide
1:06:37
Example 1: Pathway of Blood
1:12:48
Example 2: Oxygenated Blood, Pacemaker, and Clotting
1:15:24
Example 3: Vasodilation and Vasoconstriction
1:16:19
Example 4: Oxygen-Hemoglobin Dissociation Curve
1:18:13
The Digestive System

56m 11s

Intro
0:00
Introduction to Digestion
0:07
Digestive Process
0:08
Intracellular Digestion
0:45
Extracellular Digestion
1:44
Types of Digestive Tracts
2:08
Gastrovascular Cavity
2:09
Complete Gastrointestinal Tract (Alimentary Canal)
3:54
'Crop'
4:43
The Human Digestive System
5:41
Structures of the Human Digestive System
5:47
The Oral Cavity and Esophagus
7:47
Mechanical & Chemical Digestion
7:48
Salivary Glands
8:55
Pharynx and Epigloltis
9:43
Peristalsis
11:35
The Stomach
12:57
Lower Esophageal Sphincter
13:00
Gastric Gland, Parietal Cells, and Pepsin
14:32
Mucus Cell
15:48
Chyme & Pyloric Sphincter
17:32
The Pancreas
18:31
Endocrine and Exocrine
19:03
Amylase
20:05
Proteases
20:51
Lipases
22:20
The Liver
23:08
The Liver & Production of Bile
23:09
The Small Intestine
24:37
The Small Intestine
24:38
Duodenum
27:44
Intestinal Enzymes
28:41
Digestive Enzyme
33:30
Site of Production: Mouth
33:43
Site of Production: Stomach
34:03
Site of Production: Pancreas
34:16
Site of Production: Small Intestine
36:18
Absorption of Nutrients
37:51
Absorption of Nutrients: Jejunum and Ileum
37:52
The Large Intestine
44:52
The Large Intestine: Colon, Cecum, and Rectum
44:53
Regulation of Digestion by Hormones
46:55
Gastrin
47:21
Secretin
47:50
Cholecystokinin (CCK)
48:00
Example 1: Intestinal Cell, Bile, and Digestion of Fats
48:29
Example 2: Matching
51:06
Example 3: Digestion and Absorption of Starch
52:18
Example 4: Large Intestine and Gastric Fluids
54:52
The Excretory System

1h 12m 14s

Intro
0:00
Nitrogenous Wastes
0:08
Nitrogenous Wastes Overview
0:09
NH3
0:39
Urea
2:43
Uric Acid
3:31
Osmoregulation
4:56
Osmoregulation
5:05
Saltwater Fish vs. Freshwater Fish
8:58
Types of Excretory Systems
13:42
Protonephridia
13:50
Metanephridia
16:15
Malpighian Tubule
19:05
The Human Excretory System
20:45
Kidney, Ureter, bladder, Urethra, Medula, and Cortex
20:53
Filtration, Reabsorption and Secretion
22:53
Filtration
22:54
Reabsorption
24:16
Secretion
25:20
The Nephron
26:23
The Nephron
26:24
The Nephron, cont.
41:45
Descending Loop of Henle
41:46
Ascending Loop of Henle
45:45
Antidiuretic Hormone
54:30
Antidiuretic Hormone (ADH)
54:31
Aldosterone
58:58
Aldosterone
58:59
Example 1: Nephron of an Aquatic Mammal
1:04:21
Example 2: Uric Acid & Saltwater Fish
1:06:36
Example 3: Nephron
1:09:14
Example 4: Gastrointestinal Infection
1:10:41
The Endocrine System

51m 12s

Intro
0:00
The Endocrine System Overview
0:07
Thyroid
0:08
Exocrine
1:56
Pancreas
2:44
Paracrine Signaling
4:06
Pheromones
5:15
Mechanisms of Hormone Action
6:06
Reception, Transduction, and Response
7:06
Classes of Hormone
10:05
Negative Feedback: Testosterone Example
12:16
The Pancreas
15:11
The Pancreas & islets of Langerhan
15:12
Insulin
16:02
Glucagon
17:28
The Anterior Pituitary
19:25
Thyroid Stimulating Hormone
20:24
Adrenocorticotropic Hormone
21:16
Follide Stimulating Hormone
22:04
Luteinizing Hormone
22:45
Growth Hormone
23:45
Prolactin
24:24
Melanocyte Stimulating Hormone
24:55
The Hypothalamus and Posterior Pituitary
25:45
Hypothalamus, Oxytocin, Antidiuretic Hormone (ADH), and Posterior Pituitary
25:46
The Adrenal Glands
31:20
Adrenal Cortex
31:56
Adrenal Medulla
34:29
The Thyroid
35:54
Thyroxine
36:09
Calcitonin
40:27
The Parathyroids
41:44
Parathyroids Hormone (PTH)
41:45
The Ovaries and Testes
43:32
Estrogen, Progesterone, and Testosterone
43:33
Example 1: Match the Following Hormones with their Descriptions
45:38
Example 2: Pancreas, Endocrine Organ & Exocrine Organ
47:06
Example 3: Insulin and Glucagon
48:28
Example 4: Increased Level of Cortisol in Blood
50:25
The Nervous System

1h 10m 38s

Intro
0:00
Types of Nervous Systems
0:28
Nerve Net
0:37
Flatworm
1:07
Cephalization
1:52
Arthropods
2:44
Echinoderms
3:11
Nervous System Organization
3:40
Nervous System Organization Overview
3:41
Automatic Nervous System: Sympathetic & Parasympathetic
4:42
Neuron Structure
6:57
Cell Body & Dendrites
7:16
Axon & Axon Hillock
8:20
Synaptic Terminals, Mylenin, and Nodes of Ranvier
9:01
Pre-synaptic and Post-synaptic Cells
10:16
Pre-synaptic Cells
10:17
Post-synaptic Cells
11:05
Types of Neurons
11:50
Sensory Neurons
11:54
Motor Neurons
13:12
Interneurons
14:24
Resting Potential
15:14
Membrane Potential
15:25
Resting Potential: Chemical Gradient
16:06
Resting Potential: Electrical Gradient
19:18
Gated Ion Channels
24:40
Voltage-Gated & Ligand-Gated Ion Channels
24:48
Action Potential
30:09
Action Potential Overview
30:10
Step 1
32:07
Step 2
32:17
Step 3
33:12
Step 4
35:14
Step 5
36:39
Action Potential Transmission
39:04
Action Potential Transmission
39:05
Speed of Conduction
41:19
Saltatory Conduction
42:58
The Synapse
44:17
The Synapse: Presynaptic & Postsynaptic Cell
44:31
Examples of Neurotransmitters
50:05
Brain Structure
51:57
Meniges
52:19
Cerebrum
52:56
Corpus Callosum
53:13
Gray & White Matter
53:38
Cerebral Lobes
55:35
Cerebellum
56:00
Brainstem
56:30
Medulla
56:51
Pons
57:22
Midbrain
57:55
Thalamus
58:25
Hypothalamus
58:58
Ventricles
59:51
The Spinal Cord
1:00:29
Sensory Stimuli
1:00:30
Reflex Arc
1:01:41
Example 1: Automatic Nervous System
1:04:38
Example 2: Synaptic Terminal and the Release of Neurotransmitters
1:06:22
Example 3: Volted-Gated Ion Channels
1:08:00
Example 4: Neuron Structure
1:09:26
Musculoskeletal System

39m 29s

Intro
0:00
Skeletal System Types and Function
0:30
Skeletal System
0:31
Exoskeleton
1:34
Endoskeleton
2:32
Skeletal System Components
2:55
Bone
3:06
Cartilage
5:04
Tendons
6:18
Ligaments
6:34
Skeletal Muscle
6:52
Skeletal Muscle
7:24
Sarcomere
9:50
The Sliding Filament Theory
13:12
The Sliding Filament Theory: Muscle Contraction
13:13
The Neuromuscular Junction
17:24
The Neuromuscular Junction: Motor Neuron & Muscle Fiber
17:26
Sarcolemma, Sarcoplasmic
21:54
Tropomyosin & Troponin
23:35
Summation and Tetanus
25:26
Single Twitch, Summation of Two Twitches, and Tetanus
25:27
Smooth Muscle
28:50
Smooth Muscle
28:58
Cardiac Muscle
30:40
Cardiac Muscle
30:42
Summary of Muscle Types
32:07
Summary of Muscle Types
32:08
Example 1: Contraction and Skeletal Muscle
33:15
Example 2: Skeletal Muscle and Smooth Muscle
36:23
Example 3: Muscle Contraction, Bone, and Nonvascularized Connective Tissue
37:31
Example 4: Sarcomere
38:17
The Immune System

1h 24m 28s

Intro
0:00
The Lymphatic System
0:16
The Lymphatic System Overview
0:17
Function 1
1:23
Function 2
2:27
Barrier Defenses
3:41
Nonspecific vs. Specific Immune Defenses
3:42
Barrier Defenses
5:12
Nonspecific Cellular Defenses
7:50
Nonspecific Cellular Defenses Overview
7:53
Phagocytes
9:29
Neutrophils
11:43
Macrophages
12:15
Natural Killer Cells
12:55
Inflammatory Response
14:19
Complement
18:16
Interferons
18:40
Specific Defenses - Acquired Immunity
20:12
T lymphocytes and B lymphocytes
20:13
B Cells
23:35
B Cells & Humoral Immunity
23:41
Clonal Selection
29:50
Clonal Selection
29:51
Primary Immune Response
34:28
Secondary Immune Response
35:31
Cytotoxic T Cells
38:41
Helper T Cells
39:20
Major Histocompatibility Complex Molecules
40:44
Major Histocompatibility Complex Molecules
40:55
Helper T Cells
52:36
Helper T Cells
52:37
Mechanisms of Antibody Action
59:00
Mechanisms of Antibody Action
59:01
Opsonization
1:00:01
Complement System
1:01:57
Classes of Antibodies
1:02:45
IgM
1:03:01
IgA
1:03:17
IgG
1:03:53
IgE
1:04:10
Passive and Active Immunity
1:05:00
Passive Immunity
1:05:01
Active Immunity
1:07:49
Recognition of Self and Non-Self
1:09:32
Recognition of Self and Non-Self
1:09:33
Self-Tolerance & Autoimmune Diseases
1:10:50
Immunodeficiency
1:13:27
Immunodeficiency
1:13:28
Chemotherapy
1:13:56
AID
1:14:27
Example 1: Match the Following Terms with their Descriptions
1:15:26
Example 2: Three Components of Non-specific Immunity
1:17:59
Example 3: Immunodeficient
1:21:19
Example 4: Self-tolerance and Autoimmune Diseases
1:23:07
Section 11: Animal Reproduction and Development
Reproduction

1h 1m 41s

Intro
0:00
Asexual Reproduction
0:17
Fragmentation
0:53
Fission
1:54
Parthenogenesis
2:38
Sexual Reproduction
4:00
Sexual Reproduction
4:01
Hermaphrodite
8:08
The Male Reproduction System
8:54
Seminiferous Tubules & Leydig Cells
8:55
Epididymis
9:48
Seminal Vesicle
11:19
Bulbourethral
12:37
The Female Reproductive System
13:25
Ovaries
13:28
Fallopian
14:50
Endometrium, Uterus, Cilia, and Cervix
15:03
Mammary Glands
16:44
Spermatogenesis
17:08
Spermatogenesis
17:09
Oogenesis
21:01
Oogenesis
21:02
The Menstrual Cycle
27:56
The Menstrual Cycle: Ovarian and Uterine Cycle
27:57
Summary of the Ovarian and Uterine Cycles
42:54
Ovarian
42:55
Uterine
44:51
Oxytocin and Prolactin
46:33
Oxytocin
46:34
Prolactin
47:00
Regulation of the Male Reproductive System
47:28
Hormones: GnRH, LH, FSH, and Testosterone
47:29
Fertilization
50:11
Fertilization
50:12
Structures of Egg
50:28
Acrosomal Reaction
51:36
Cortical Reaction
53:09
Example 1: List Three Differences between Spermatogenesis and oogenesis
55:36
Example 2: Match the Following Terms to their Descriptions
57:34
Example 3: Pregnancy and the Ovarian Cycle
58:44
Example 4: Hormone
1:00:43
Development

50m 5s

Intro
0:00
Cleavage
0:31
Cleavage
0:32
Meroblastic
2:06
Holoblastic Cleavage
3:23
Protostomes
4:34
Deuterostomes
5:13
Totipotent
5:52
Blastula Formation
6:42
Blastula
6:46
Gastrula Formation
8:12
Deuterostomes
11:02
Protostome
11:44
Ectoderm
12:17
Mesoderm
12:55
Endoderm
13:40
Cytoplasmic Determinants
15:19
Cytoplasmic Determinants
15:23
The Bird Embryo
22:52
Cleavage
23:35
Blastoderm
23:55
Primitive Streak
25:38
Migration and Differentiation
27:09
Extraembryonic Membranes
28:33
Extraembryonic Membranes
28:34
Chorion
30:02
Yolk Sac
30:36
Allantois
31:04
The Mammalian Embryo
32:18
Cleavage
32:28
Blastocyst
32:44
Trophoblast
34:37
Following Implantation
35:48
Organogenesis
37:04
Organogenesis, Notochord and Neural Tube
37:05
Induction
40:15
Induction
40:39
Fate Mapping
41:40
Example 1: Processes and Stages of Embryological Development
42:49
Example 2: Transplanted Cells
44:33
Example 3: Germ Layer
46:41
Example 4: Extraembryonic Membranes
47:28
Section 12: Animal Behavior
Animal Behavior

47m 48s

Intro
0:00
Introduction to Animal Behavior
0:05
Introduction to Animal Behavior
0:06
Ethology
1:04
Proximate Cause & Ultimate Cause
1:46
Fixed Action Pattern
3:07
Sign Stimulus
3:40
Releases and Example
3:55
Exploitation and Example
7:23
Learning
8:56
Habituation, Associative Learning, and Imprinting
8:57
Habituation
10:03
Habituation: Definition and Example
10:04
Associative Learning
11:47
Classical
12:19
Operant Conditioning
13:40
Positive & Negative Reinforcement
14:59
Positive & Negative Punishment
16:13
Extinction
17:28
Imprinting
17:47
Imprinting: Definition and Example
17:48
Social Behavior
20:12
Cooperation
20:38
Agonistic
21:37
Dorminance Heirarchies
23:23
Territoriality
24:08
Altruism
24:55
Communication
26:56
Communication
26:57
Mating
32:38
Mating Overview
32:40
Promiscuous
33:13
Monogamous
33:32
Polygamous
33:48
Intrasexual
34:22
Intersexual Selection
35:08
Foraging
36:08
Optimal Foraging Model
36:39
Foraging
37:47
Movement
39:12
Kinesis
39:20
Taxis
40:17
Migration
40:54
Lunar Cycles
42:02
Lunar Cycles
42:08
Example 1: Types of Conditioning
43:19
Example 2: Match the Following Terms to their Descriptions
44:12
Example 3: How is the Optimal Foraging Model Used to Explain Foraging Behavior
45:47
Example 4: Learning
46:54
Section 13: Ecology
Biomes

58m 49s

Intro
0:00
Ecology
0:08
Ecology
0:14
Environment
0:22
Integrates
1:41
Environment Impacts
2:20
Population and Distribution
3:20
Population
3:21
Range
4:50
Potential Range
5:10
Abiotic
5:46
Biotic
6:22
Climate
7:55
Temperature
8:40
Precipitation
10:00
Wind
10:37
Sunlight
10:54
Macroclimates & Microclimates
11:31
Other Abiotic Factors
12:20
Geography
12:28
Water
13:17
Soil and Rocks
13:48
Sunlight
14:42
Sunlight
14:43
Seasons
15:43
June Solstice, December Solstice, March Equinox, and September Equinox
15:44
Tropics
19:00
Seasonability
19:39
Wind and Weather Patterns
20:44
Vertical Circulation
20:51
Surface Wind Patterns
25:18
Local Climate Effects
26:51
Local Climate Effects
26:52
Terrestrial Biomes
30:04
Biome
30:05
Forest
31:02
Tropical Forest
32:00
Tropical Forest
32:01
Temperate Broadleaf Forest
32:55
Temperate Broadleaf Forest
32:56
Coniferous/Taiga Forest
34:10
Coniferous/Taiga Forest
34:11
Desert
36:05
Desert
36:06
Grassland
37:45
Grassland
37:46
Tundra
40:09
Tundra
40:10
Freshwater Biomes
42:25
Freshwater Biomes: Zones
42:27
Eutrophic Lakes
44:24
Oligotrophic Lakes
45:01
Lakes Turnover
46:03
Rivers
46:51
Wetlands
47:40
Estuary
48:11
Marine Biomes
48:45
Marine Biomes: Zones
48:46
Example 1: Diversity of Life
52:18
Example 2: Marine Biome
53:08
Example 3: Season
54:20
Example 4: Biotic vs. Abiotic
55:54
Population

41m 16s

Intro
0:00
Population
0:07
Size 'N'
0:16
Density
0:41
Dispersion
1:01
Measure Population: Count Individuals, Sampling, and Proxymeasure
2:26
Mortality
7:29
Mortality and Survivorship
7:30
Age Structure Diagrams
11:52
Expanding with Rapid Growth, Expanding, and Stable
11:58
Population Growth
15:39
Biotic Potential & Exponential Growth
15:43
Logistic Population Growth
19:07
Carrying Capacity (K)
19:18
Limiting Factors
20:55
Logistic Model and Oscillation
22:55
Logistic Model and Oscillation
22:56
Changes to the Carrying Capacity
24:36
Changes to the Carrying Capacity
24:37
Growth Strategies
26:07
'r-selected' or 'r-strategist'
26:23
'K-selected' or 'K-strategist'
27:47
Human Population
30:15
Human Population and Exponential Growth
30:21
Case Study - Lynx and Hare
31:54
Case Study - Lynx and Hare
31:55
Example 1: Estimating Population Size
34:35
Example 2: Population Growth
36:45
Example 3: Carrying Capacity
38:17
Example 4: Types of Dispersion
40:15
Communities

1h 6m 26s

Intro
0:00
Community
0:07
Ecosystem
0:40
Interspecific Interactions
1:14
Competition
2:45
Competition Overview
2:46
Competitive Exclusion
3:57
Resource Partitioning
4:45
Character Displacement
6:22
Predation
7:46
Predation
7:47
True Predation
8:05
Grazing/ Herbivory
8:39
Predator Adaptation
10:13
Predator Strategies
10:22
Physical Features
11:02
Prey Adaptation
12:14
Prey Adaptation
12:23
Aposematic Coloration
13:35
Batesian Mimicry
14:32
Size
15:42
Parasitism
16:48
Symbiotic Relationship
16:54
Ectoparasites
18:31
Endoparasites
18:53
Hyperparisitism
19:21
Vector
20:08
Parasitoids
20:54
Mutualism
21:23
Resource - Resource mutualism
21:34
Service - Resource Mutualism
23:31
Service - Service Mutualism: Obligate & Facultative
24:23
Commensalism
26:01
Commensalism
26:03
Symbiosis
27:31
Trophic Structure
28:35
Producers & Consumers: Autotrophs & Heterotrophs
28:36
Food Chain
33:26
Producer & Consumers
33:38
Food Web
39:01
Food Web
39:06
Significant Species within Communities
41:42
Dominant Species
41:50
Keystone Species
42:44
Foundation Species
43:41
Community Dynamics and Disturbances
44:31
Disturbances
44:33
Duration
47:01
Areal Coverage
47:22
Frequency
47:48
Intensity
48:04
Intermediate Level of Disturbance
48:20
Ecological Succession
50:29
Primary and Secondary Ecological Succession
50:30
Example 1: Competition Situation & Outcome
57:18
Example 2: Food Chains
1:00:08
Example 3: Ecological Units
1:02:44
Example 4: Disturbances & Returning to the Original Climax Community
1:04:30
Energy and Ecosystems

57m 42s

Intro
0:00
Ecosystem: Biotic & Abiotic Components
0:15
First Law of Thermodynamics & Energy Flow
0:40
Gross Primary Productivity (GPP)
3:52
Net Primary Productivity (NPP)
4:50
Biogeochemical Cycles
7:16
Law of Conservation of Mass & Biogeochemical Cycles
7:17
Water Cycle
10:55
Water Cycle
10:57
Carbon Cycle
17:52
Carbon Cycle
17:53
Nitrogen Cycle
22:40
Nitrogen Cycle
22:41
Phosphorous Cycle
29:34
Phosphorous Cycle
29:35
Climate Change
33:20
Climate Change
33:21
Eutrophication
39:38
Nitrogen
40:34
Phosphorous
41:29
Eutrophication
42:55
Example 1: Energy and Ecosystems
45:28
Example 2: Atmospheric CO2
48:44
Example 3: Nitrogen Cycle
51:22
Example 4: Conversion of a Forest near a Lake to Farmland
53:20
Section 14: Laboratory Review
Laboratory Review

2h 4m 30s

Intro
0:00
Lab 1: Diffusion and Osmosis
0:09
Lab 1: Diffusion and Osmosis
0:10
Lab 1: Water Potential
11:55
Lab 1: Water Potential
11:56
Lab 2: Enzyme Catalysis
18:30
Lab 2: Enzyme Catalysis
18:31
Lab 3: Mitosis and Meiosis
27:40
Lab 3: Mitosis and Meiosis
27:41
Lab 3: Mitosis and Meiosis
31:50
Ascomycota Life Cycle
31:51
Lab 4: Plant Pigments and Photosynthesis
40:36
Lab 4: Plant Pigments and Photosynthesis
40:37
Lab 5: Cell Respiration
49:56
Lab 5: Cell Respiration
49:57
Lab 6: Molecular Biology
55:06
Lab 6: Molecular Biology & Transformation 1st Part
55:07
Lab 6: Molecular Biology
1:01:16
Lab 6: Molecular Biology 2nd Part
1:01:17
Lab 7: Genetics of Organisms
1:07:32
Lab 7: Genetics of Organisms
1:07:33
Lab 7: Chi-square Analysis
1:13:00
Lab 7: Chi-square Analysis
1:13:03
Lab 8: Population Genetics and Evolution
1:20:41
Lab 8: Population Genetics and Evolution
1:20:42
Lab 9: Transpiration
1:24:02
Lab 9: Transpiration
1:24:03
Lab 10: Physiology of the Circulatory System
1:31:05
Lab 10: Physiology of the Circulatory System
1:31:06
Lab 10: Temperature and Metabolism in Ectotherms
1:38:25
Lab 10: Temperature and Metabolism in Ectotherms
1:38:30
Lab 11: Animal Behavior
1:40:52
Lab 11: Animal Behavior
1:40:53
Lab 12: Dissolved Oxygen & Aquatic Primary Productivity
1:45:36
Lab 12: Dissolved Oxygen & Aquatic Primary Productivity
1:45:37
Lab 12: Primary Productivity
1:49:06
Lab 12: Primary Productivity
1:49:07
Example 1: Chi-square Analysis
1:56:31
Example 2: Mitosis
1:59:28
Example 3: Transpiration of Plants
2:00:27
Example 4: Population Genetic
2:01:16
Section 15: The AP Biology Test
Understanding the Basics

13m 2s

Intro
0:00
AP Biology Structure
0:18
Section I
0:31
Section II
1:16
Scoring
2:04
The Four 'Big Ideas'
3:51
Process of Evolution
4:37
Biological Systems Utilize
4:44
Living Systems
4:55
Biological Systems Interact
5:03
Items to Bring to the Test
7:56
Test Taking Tips
9:53
Section 16: Practice Test (Barron's 4th Edition)
AP Biology Practice Exam: Section I, Part A, Multiple Choice Questions 1-31

1h 4m 29s

Intro
0:00
AP Biology Practice Exam
0:14
Multiple Choice 1
0:40
Multiple Choice 2
2:27
Multiple Choice 3
4:30
Multiple Choice 4
6:43
Multiple Choice 5
9:27
Multiple Choice 6
11:32
Multiple Choice 7
12:54
Multiple Choice 8
14:42
Multiple Choice 9
17:06
Multiple Choice 10
18:42
Multiple Choice 11
20:49
Multiple Choice 12
23:23
Multiple Choice 13
26:20
Multiple Choice 14
27:52
Multiple Choice 15
28:44
Multiple Choice 16
33:07
Multiple Choice 17
35:31
Multiple Choice 18
39:43
Multiple Choice 19
40:37
Multiple Choice 20
42:47
Multiple Choice 21
45:58
Multiple Choice 22
49:49
Multiple Choice 23
53:44
Multiple Choice 24
55:12
Multiple Choice 25
55:59
Multiple Choice 26
56:50
Multiple Choice 27
58:08
Multiple Choice 28
59:54
Multiple Choice 29
1:01:36
Multiple Choice 30
1:02:31
Multiple Choice 31
1:03:50
AP Biology Practice Exam: Section I, Part A, Multiple Choice Questions 32-63

50m 44s

Intro
0:00
AP Biology Practice Exam
0:14
Multiple Choice 32
0:27
Multiple Choice 33
4:14
Multiple Choice 34
5:12
Multiple Choice 35
6:51
Multiple Choice 36
10:46
Multiple Choice 37
11:27
Multiple Choice 38
12:17
Multiple Choice 39
13:49
Multiple Choice 40
17:02
Multiple Choice 41
18:27
Multiple Choice 42
19:35
Multiple Choice 43
21:10
Multiple Choice 44
23:35
Multiple Choice 45
25:00
Multiple Choice 46
26:20
Multiple Choice 47
28:40
Multiple Choice 48
30:14
Multiple Choice 49
31:24
Multiple Choice 50
32:45
Multiple Choice 51
33:41
Multiple Choice 52
34:40
Multiple Choice 53
36:12
Multiple Choice 54
38:06
Multiple Choice 55
38:37
Multiple Choice 56
40:00
Multiple Choice 57
41:18
Multiple Choice 58
43:12
Multiple Choice 59
44:25
Multiple Choice 60
45:02
Multiple Choice 61
46:10
Multiple Choice 62
47:54
Multiple Choice 63
49:01
AP Biology Practice Exam: Section I, Part B, Grid In

21m 52s

Intro
0:00
AP Biology Practice Exam
0:17
Grid In Question 1
0:29
Grid In Question 2
3:49
Grid In Question 3
11:04
Grid In Question 4
13:18
Grid In Question 5
17:01
Grid In Question 6
19:30
AP Biology Practice Exam: Section II, Long Free Response Questions

31m 22s

Intro
0:00
AP Biology Practice Exam
0:18
Free Response 1
0:29
Free Response 2
20:47
AP Biology Practice Exam: Section II, Short Free Response Questions

24m 41s

Intro
0:00
AP Biology Practice Exam
0:15
Free Response 3
0:26
Free Response 4
5:21
Free Response 5
8:25
Free Response 6
11:38
Free Response 7
14:48
Free Response 8
22:14
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Lecture Comments (11)

0 answers

Post by Quazi Niloy on December 15, 2014

Hello Dr. Eaton

I hope all is well

Around 62:80 you put grey matter is inside and white matter is outside. This is a contradiction to your earlier statements

I hope you can fix the problem.

Thanks
Quazi Niloy

1 answer

Last reply by: Dr Carleen Eaton
Tue Mar 12, 2013 1:07 AM

Post by Joao Carlos Gomes Neto on March 10, 2013

Hi, I cant watch from the point where you start talking about the thyroid. The video always goes back to the introduction again.

Thanks

1 answer

Last reply by: Dr Carleen Eaton
Thu Jun 21, 2012 12:22 PM

Post by Vinh Dong on June 1, 2012

Thank you so much for these lectures. I'm using these lectures as a basic foundation for MCAT study, and so far I'm doing better on my practice tests. These lectures are hopefully my secret weapon into getting into medical school.

1 answer

Last reply by: Dr Carleen Eaton
Sat Feb 4, 2012 4:34 PM

Post by Dorine Lantimo on February 3, 2012

Do men produce oxcytocin?

1 answer

Last reply by: Basil Khuder
Sat Nov 24, 2012 8:04 PM

Post by Senghuot Lim on June 12, 2011

i know that she's smart and all. however, she speaks and write fast...i'm okay with it...but i would suggest her to slow down a bit because most people that pay money here are usually have trouble in class or need more resource other than the teachers or books.

1 answer

Last reply by: Dr Carleen Eaton
Sun Apr 17, 2011 4:46 PM

Post by Billy Jay on April 17, 2011

I don't see the Reproduction Lecture. Any idea when it'll be posted? Thanks.

The Endocrine System

  • Endocrine glands secrete hormones into the bloodstream. Hormones exert effects on target cells.
  • The pancreas produces insulin and glucagon. Insulin decreases the level of glucose in the blood, whereas glucagon increases the level of glucose in the blood.
  • The secretion of hormones by the anterior pituitary gland is regulated by the hypothalamus. The hypothalamus also produces oxytocin and antidiuretic hormone (ADH), which are stored in and secreted by the posterior pituitary.
  • The anterior pituitary secretes hormones, called tropic hormones, that act on other endocrine glands as well as hormones with direct physiological effects.
  • The adrenal cortex secretes mineralocorticoids and glucocorticoids. The adrenal medulla secretes epinephrine and norepinephrine, which trigger the fight or flight response.
  • The thyroid produces thyroxine, which increases the metabolic rate, and calcitonin, which lowers blood calcium levels.
  • Parathyroid hormone is released by the parathyroid glands in response to decreased blood calcium levels. PTH stimulates the release of stored calcium from the bones.
  • The ovaries produce estrogen and progesterone. Estrogen is responsible for the development of secondary sex characteristics in females. Progesterone maintains pregnancy.
  • The testes secrete testosterone, which stimulates the development of male secondary sex characteristics.

The Endocrine System

Lecture Slides are screen-captured images of important points in the lecture. Students can download and print out these lecture slide images to do practice problems as well as take notes while watching the lecture.

  • Intro 0:00
  • The Endocrine System Overview 0:07
    • Thyroid
    • Exocrine
    • Pancreas
    • Paracrine Signaling
    • Pheromones
  • Mechanisms of Hormone Action 6:06
    • Reception, Transduction, and Response
    • Classes of Hormone
    • Negative Feedback: Testosterone Example
  • The Pancreas 15:11
    • The Pancreas & islets of Langerhan
    • Insulin
    • Glucagon
  • The Anterior Pituitary 19:25
    • Thyroid Stimulating Hormone
    • Adrenocorticotropic Hormone
    • Follide Stimulating Hormone
    • Luteinizing Hormone
    • Growth Hormone
    • Prolactin
    • Melanocyte Stimulating Hormone
  • The Hypothalamus and Posterior Pituitary 25:45
    • Hypothalamus, Oxytocin, Antidiuretic Hormone (ADH), and Posterior Pituitary
  • The Adrenal Glands 31:20
    • Adrenal Cortex
    • Adrenal Medulla
  • The Thyroid 35:54
    • Thyroxine
    • Calcitonin
  • The Parathyroids 41:44
    • Parathyroids Hormone (PTH)
  • The Ovaries and Testes 43:32
    • Estrogen, Progesterone, and Testosterone
  • Example 1: Match the Following Hormones with their Descriptions 45:38
  • Example 2: Pancreas, Endocrine Organ & Exocrine Organ 47:06
  • Example 3: Insulin and Glucagon 48:28
  • Example 4: Increased Level of Cortisol in Blood 50:25

Transcription: The Endocrine System

Welcome to Educator.com.0000

In this section of animal physiology, we will be focusing on the endocrine system.0002

Hormones are molecules that are released by endocrine glands, and they travel via the blood stream to illicit a response from distant target tissues.0010

To understand endocrine glands, we use an example, and an example would be the thyroid gland.0023

The thyroid, which we will talk about in more detail later, secretes thyroxin or thyroid hormone into the blood stream.0028

And thyroxin goes on to affect target tissues and organs.0039

And the effect that it has on a tissue or organ maybe different depending on what type of tissue it is, so the results are overall an increase in metabolism.0050

And that results in an increase in temperature, heart rate and changes in other physiological processes.0062

So, one hormone can have multiple effects in the body.0071

Endocrine glands secrete substances, secrete hormones, into the extracellular fluid.0076

From the extracellular fluid, the hormone diffuses into the blood stream.0084

So, here, I am talking about thyroxin being secreted into the blood stream, but to get a little more subtle about it,0090

what happens is that the hormone is secreted by the thyroid cells into the fluid surrounding the cells0095

and then, from there, can diffuse into the blood stream and then, be delivered throughout the body.0102

Although, the hormone will go throughout the body via the blood stream,0108

it is only going to affect target tissues that have a receptor for that particular hormone.0111

Exocrine organs or exocrine glands secrete substances via ducts. They secrete them via ducts- secrete substances into ducts.0119

So, it is exocrine, whereas, endocrine glands secrete substances into the blood stream.0133

Recall that we talked about the pancreas when we covered the GI tract, when we covered the digestive system.0145

And I said that the pancreas is both an exocrine organ and an endocrine organ.0151

So, to give you another example of an exocrine gland- sweat glands, salivary glands. They secrete substances into ducts.0157

Now, the pancreas, as we will talk about shortly, is both an exocrine gland and an endocrine gland.0164

And its exocrine function is that it secretes digestive enzymes via the pancreatic duct into the small intestine such as lipases and amylase.0181

However, it also secretes - so this is digestive enzymes via ducts - hormones -0192

we will talk specifically about these hormones, insulin and glucagon - into the blood stream.0203

So, the pancreas is actually both an exocrine gland and an endocrine gland.0208

Hormones have many different effects. Growth hormone regulates growth, as the name suggests.0213

Estrogen and testosterone affect development and reproduction. They stimulate the formation of gametes.0221

Other hormones like insulin and glucagon regulate blood glucose level. Calcium levels, metabolism as I mentioned, these are all regulated by hormones.0228

Before we go on and talk in detail about hormones and the endocrine system, I want to mention a couple of other terms you should be familiar with.0239

Endocrine system is one way of signaling. The nervous system is another method that the body has for signaling and coordinating activity.0248

A third mechanism is what is called paracrine signaling, and in paracrine signaling, a substance is released by an organ; but it affects only nearby cells.0257

So, this is local regulation, so a substance secreted and affects nearby cells. It diffuses over and affects only cells nearby.0269

This is endocrine signaling where the substance is released, but it diffuses into the blood stream and can go all over the body. That is endocrine.0286

Whereas, in paracrine, I have an organ with cells, and it is secreting substances; and these substances only affect other cells that are nearby.0296

They are not going to go out into the blood stream and go all over the body.0308

Finally, pheromones also are involved in signaling, and these are a means of communication, but often, it is to signal members of the same species.0314

For example, pheromones may be used to mark territory for an animal or to attract a mate.0334

So, these are method of communication that is not just within the body.0342

But, it can also signal another member of the species that it is that individual's territory, or that individual is available for mating, to attract a mate.0348

So, this is another type of signaling.0359

OK, now, I am going to review mechanisms of hormone action, and we talked about this in detail in the lecture on intercellular communication.0365

If you have not already watched that, I suggest that you watch that.0378

However, I am going to review the major points so that you can understand endocrine action.0382

In this lecture though, we are going to focus more on specific endocrine organs, the hormones they secrete and the effects of those hormones.0386

But just looking at the molecular mechanism of hormone action, as I said,0395

cells can communicate with each other through both electrical signals as with the nervous system and through chemical systems.0400

And hormones are a chemical signal, so substances released from one cell such as a cell in the thyroid gland.0408

Thyroxin is released, travel and go through a several step pathway to illicit a response in the target cell.0417

Now, there is two major mechanisms of action. I am going to talk about the first one here where it is a more complex pathway.0426

And this pathway, there are several steps. The first one is the reception of the signal.0435

The second is the transduction of the signal, and the third is the response phase.0447

Recall that in the first step, the ligand, which is a molecule that binds to a target cell, reaches the target cell, binds to the receptor.0456

So, that is the reception phase, and right now, I am just looking at extracellular receptors, receptors that in the cell membrane.0473

But, we will talk about intracellular receptor soon, so this first phase is binding.0481

This binding often causes a...so, it binds, and the result is a conformational change in the receptor that may activate another molecule.0486

So, there might be a conformational change in this receptor that causes it to be able to bind this molecule.0497

This molecule may in turn activate via an enzyme that activates another molecule that, then, cleaves another molecule and on down.0504

And what this second phase is, is cascade of one molecule activating another molecule is transduction.0511

Recall, we talked about signal transduction pathways.0518

And during these pathways, the message is passed from the exterior of the cell to the interior and at the same time, the signal is amplified.0522

And signal transduction pathways often involve, so this step two often involves second messengers such as cyclic AMP or IP3 or diacylglycerol.0533

So, first phase, the signal is received.0552

The second phase, the signal is transduced or sent from the place where it has been received to the interior of the cell.0555

Finally, that message is passed all the way to the interior.0564

And here, we have the nucleus, and what this message may do is result in increasing the level of transcription of a gene.0568

It may decrease the level of transcription of a gene, or it may act on the protein level, so gene or protein level.0577

So, the response maybe to activate an existing protein or inactivate it.0587

Now, this is the situation for the extracellular receptor. However, some hormones can cross the cell membrane.0595

There are several major classes of hormones. Two, in particular, that we will focus on, the first two, the first one are steroid hormones.0606

Now, steroid hormones are derived from cholesterol. Therefore, they are fat soluble.0618

They can cross the cell membrane. An example is the hormone cortisol.0624

The second class of hormones are the peptide hormones.0631

The peptide hormones are generally insoluble to the cell membrane, so cannot cross the cell membrane. An example is insulin.0635

There is a third class of hormones that are amine hormones derived from the amino acid tyrosine, and sometimes these are fat soluble.0653

Some can cross the cell membrane. Others cannot, so it depends on this one.0662

A peptide hormone is going to have to bind to an extracellular receptor and use signal transduction to get its message into the interior of the cell.0670

Now, the situation is different for a steroid hormone.0679

For a steroid hormone, the receptor might actually be here inside the cell, and then, this steroid hormone can enter the cell,0682

bind to the receptor, travel to the nucleus and act directly as an initiator of transcription or to shut off transcription, sometimes, even permanently.0693

It does not need to use this mediator of a signal cascade. In fact, some steroid hormones even have receptors that are in the nucleus.0707

So, what will happen is, the hormone will travel in, bind, and it is already ready to go to activate or turn off transcription.0718

These are two mechanisms of hormone action.0731

Another topic involving mechanism of hormone actions is the idea of negative feedback inhibition.0739

We have touched upon negative feedback a few times in the course.0749

But, just to remind you how this would work and put it in the context of hormones, is that the production of a hormone will cause a response.0753

That response in negative feedback or some aspect of that response will turn around and0764

decrease the production of the hormone so that you will not end up with too much hormone.0772

You will not end up with too little. It is a loop of regulation.0779

Let me explain this, giving in an example of testosterone. Testosterone is produced by the testis, and the signals starts up here in the hypothalamus.0783

And the hypothalamus we will talk about regulates the anterior pituitary.0799

In this case, it releases a hormone called gonadotropin-releasing hormone that acts on the anterior pituitary.0804

You do not need to remember all these details right now just talking about negative feedback.0814

The anterior pituitary, then, releases luteinizing hormone, which acts on the testes, and the testes in response produce testosterone.0818

Testosterone exerts a variety of effects that we will talk about, so it exerts its effects on target organs.0833

However, it also suppresses further production of testosterone. It suppresses the hypothalamus from initiating this flow of testosterone production.0842

So, it inhibits the hypothalamus from releasing the GnRH, which will in turn cause the anterior pituitary to not release LH and on down.0861

The feedback is "alright, there is testosterone produced, turn around and stop production of more testosterone".0873

Otherwise, there would just be more and more testosterone, and there would not be anything regulating it.0883

The hypothalamus releases GnRH, and one of the results of that is testosterone. That is a response.0890

And that response goes and shuts off the initial signal.0897

We are going to now go on and talk about specific endocrine organs, and we are going to start with the pancreas, which I already mentioned briefly.0907

As I said, the pancreas is both an exocrine gland.0917

This is its function in digestion. It produces and secretes digestive enzymes via a duct and an endocrine organ.0920

In its endocrine function, the pancreas secretes two hormones.0929

And these hormones are actually produced by special groups of cells called islets of Langerhans, and there are two types.0934

There are beta cells, and the beta cells produce insulin, and the alpha cells produce glucagon.0943

These two hormones have opposing actions. They are what is called antagonistic hormones.0952

Beginning with insulin, let's say that blood glucose is high. You eat a bunch of sugary foods, and it is broken down; and blood glucose is high.0961

What this is going to do is it is going to trigger the pancreas to release insulin.0978

The effect of insulin is to bind to target cells and cause them to take up glucose, so it stimulates cells to take up glucose.0992

If the cells take the glucose up, it takes it out of the blood stream, and the result will be blood glucose is decreased.1004

So, we started out with high blood glucose. The result, the final effect of insulin is to decrease blood glucose levels.1018

And just to note that various cells can take up glucose, but in the liver, excess glucose, remember, is stored as glycogen.1026

So, that is another function of the liver. In the liver and some other cells, as well, the glucose is stored as glycogen.1034

Now, glucagon has the opposite effect. Let's say that you do not eat for a while.1050

You are getting pretty hungry. Your blood sugar gets low.1056

Now, you have blood glucose is low. That is going to stimulate the pancreas to release glucagon.1059

Glucagon tells the liver to break down the glycogen, so it stimulates the liver to break down glycogen, and the result is going to be a release of glucose.1077

The glycogen is broken down into glucose. Therefore, blood glucose is increased.1096

The effect of glucagon is to increase blood glucose. The effect of insulin is to decrease blood glucose.1104

You have probably heard of diabetes. Diabetes mellitus is a disorder in which there is either a deficiency of insulin or insulin is being produced.1114

So, there is enough insulin, but the cells are unresponsive to insulin.1127

The result of either form of diabetes is that blood glucose levels end up being too high.1131

And over time, a persistently high blood glucose level can cause damage to various organs to the kidneys, to the eyes, and to the cardiovascular system.1138

This is treated either by giving an individual insulin if they do not produce insulin or medications that allow them1147

to utilize the insulin more effectively if they are producing it, but their body is not responding to the insulin.1156

The second organ we are going to cover is the anterior pituitary, which produces many hormones.1166

The pituitary gland is located in the brain below the hypothalamus.1173

The hypothalamus regulates the anterior pituitary, and there are two parts of the pituitary: the anterior pituitary and the posterior pituitary.1179

And they have very different functions, so we are going to focus on these separately.1193

First, the anterior pituitary, and as I said, it secretes multiple hormones. Some of these hormones are what is called tropic hormones.1197

Tropic hormones act on other endocrine glands.1207

So, instead of just acting directly on a tissue like say thyroxin goes and acts on a tissues,1211

what a tropic hormone does is it acts on another endocrine organ, and then, it might stimulate the release of a hormone from that organ.1217

So, we will start out with some of the tropic hormones that are produced by the anterior pituitary for example thyroid-stimulating hormone.1225

And these are often known by their initials, so TSH. This is just often called TSH.1237

This is released from the anterior pituitary at a signal from the hypothalamus.1243

And it travels to the thyroid and stimulates the release of thyroid hormone, so stimulates the thyroid gland.1250

So, it is not having a direct effect on the physiology of the body.1262

What it is doing is stimulating another endocrine organ that will release a hormone that has physiological effects.1267

The second hormone that I am going to discuss is adrenocorticotropic hormone, and right here in the name, it tells you it is a tropic hormone.1277

ACTH stimulates the adrenal cortex, and as we are going to discuss, the adrenal gland even though it is one organ, it is almost like two glands in one.1291

The adrenal cortex and the adrenal medulla have different function, so it stimulates the adrenal cortex.1303

And the adrenal cortex in turn releases mineralocorticoids like aldosterone and glucocorticoids like cortisol.1314

The anterior pituitary also secretes hormones that are important for reproduction for example follicle-stimulating hormone, usually known as FSH.1324

It stimulates the production of gametes, so ova in females, sperm in males.1348

Luteinizing hormone, LH: this causes the rupture of the follicle in the ovary so that the ovum is released during ovulation.1366

I will just put "release of ovum", and it also stimulates the production of testosterone in males.1389

And we are actually going to talk in more detail about FSH, LH and testosterone, progesterone, estrogen in detail in a separate lecture on reproduction.1400

But for right now, you just need to know that these are released by the anterior pituitary and affect reproduction.1417

Additional hormones produced by the anterior pituitary are growth hormones, so growth hormone is not a tropic hormone. It has a direct action.1426

It stimulates the growth of bones and muscles.1440

A disorder called gigantism where people grow extremely tall can be a result of too much growth hormone.1447

There is a form of dwarfism that results from too little growth hormone and can sometimes be treated with growth hormone.1456

Prolactin: the name tells you lactin like milk, and it stimulates the development of the mammary glands1465

and also, the production of milk by the mammary glands, so stimulates development of mammary glands and milk production.1475

The last hormone we are going to talk about with the anterior pituitary is melanocyte-stimulating hormone.1497

In humans, this hormone stimulates the production of melanin, which is a pigment that is responsible for skin color, eye color, so pigment.1514

It is a pigment, so it stimulates melanin production.1525

And I do want to note that different hormones can elicit a different response in a different species.1530

So, in a human, melanocyte-stimulating hormone might have one function, and it elicits a slightly different response in another species.1537

Next, we are going to talk about the hypothalamus and the posterior pituitary glands.1548

As I mentioned, the hypothalamus regulates the anterior pituitary.1555

So, it secretes a bunch of hormones that act on the anterior pituitary, and it also secretes a couple of hormones with direct actions.1562

First, talking about regulation of the anterior pituitary, what happens is the hypothalamus releases hormones that are either stimulating or inhibiting.1570

They either stimulate or inhibit the anterior pituitary to release its hormones.1589

And this occurs by the release of the hormone from the hypothalamus into a group of capillaries.1595

So, it releases the hormone into a group of capillaries, so hypothalamus that surround it. There is a capillary network surrounding it.1603

Then, the hormones travel via the capillaries to the portal veins. It is called the portal veins.1615

And these portal veins connect to a second network of capillaries, and these capillaries surround the anterior pituitary.1621

And in that way, the hypothalamus can regulate the anterior pituitary.1632

Just to give you some examples of these hormones, one is thyrotropin-releasing hormone- TRH.1637

Another hormone that I already mentioned is...1653

So, this will act on the anterior pituitary and stimulate thyroid-stimulating hormone1657

to be released from the anterior pituitary, which will go on to stimulate the thyroid.1664

Gonadotropin-releasing hormone: GnRH stimulates the release of luteinizing hormone and follicle-stimulating hormone by the anterior pituitary.1670

There are many others. There are growth-hormone, releasing hormone, and it indicates that it stimulates the anterior pituitary to release growth hormone.1692

There is corticotropin-releasing hormone. It stimulates the release of ACTH by the anterior pituitary.1706

This is the function of the hypothalamus to regulate the anterior pituitary.1724

It is located in the brain near the pituitary, and what the hypothalamus does is it secretes...1735

The hypothalamus and the pituitary are right about in this region where the purple is.1743

So, the second function of the hypothalamus is to produce two hormones that are stored in the posterior pituitary.1748

It regulates the anterior pituitary, one function, and second function is to produce oxytocin and antidiuretic hormone.1755

These are stored in the posterior pituitary, and then, at a particular signal, they will be released or secreted by the posterior pituitary.1774

The function of oxytocin is to stimulate uterine contractions, so during child birth, the uterus will contract to cause the baby to be delivered.1791

So, it stimulates uterine contractions.1804

A second hormone, ADH, antidiuretic hormone is discussed in detail in the lecture on the excretory system.1814

But, recall briefly that what ADH does is it cause increased reabsorption of water by the kidney.1821

So, If there is an increase in osmolarity, the blood becomes more concentrated in terms of solutes that signals that the body needs to conserve water.1840

It needs to hold on to water, and that will trigger the release of ADH by the posterior pituitary,1850

which the ADH will, then, act on the kidney to cause the reabsorption of water.1858

The result is that more water will stay in the blood stream to dilute out the blood.1864

And the urine will become more concentrated thus, decreasing the loss of water into the urine.1869

OK, this was the hypothalamus and the posterior pituitary. The next set of glands we are going to talk about are the adrenal glands.1876

And the adrenal glands are located right on top of the kidneys, so on top of the kidneys, that is where they are located.1884

And the two parts of the adrenal glands, the adrenal cortex and the adrenal medulla,1895

even though they are together, they are functionally really separate endocrine glands.1902

They have separate cell types and separate hormones that they release.1905

So, these two sections are the adrenal cortex and the adrenal medulla.1911

So, the adrenal cortex, what happens is the anterior pituitary secretes adrenocorticotropic hormone, ACTH.1916

ACTH, then, acts on the adrenal cortex, and the adrenal cortex releases mineralocorticoids and glucocorticoids.1930

Mineralocorticoids are involved in maintaining sodium and water balance in the body. An example of a mineralocorticoid is aldosterone.1950

Recall that aldosterone, again, we talked about this in the lecture on the excretory system and the kidney,1964

but that aldosterone increases sodium - let's just talk about aldosterone for a minute - reabsorption in the kidney.1971

And when more sodium is reabsorbed, water will follow. So, this in turn triggers increased water reabsorption.1986

So, If an individual has low blood pressure or decreased volume, their body needs to hold on to more water.1996

So, low blood pressure, low volume, would stimulate the production and secretion of aldosterone,2005

which would signal the kidney to hold on to water to thereby, increase blood volume and blood pressure.2015

So, those are mineralocorticoids.2023

The second type of hormone produced by the adrenal cortex are the glucocorticoids.2025

An example is cortisol and the gluco right here, tells you that these are also involved in glucose regulation.2036

So, glucose levels are increased by glucocorticoids like cortisol.2047

They also have various other functions such as suppressing the immune system and the inflammatory response.2053

The second area of the adrenal glands is the adrenal medulla.2062

The adrenal medulla releases epinephrine, which is also known as adrenaline and norepinephrine or also known as noradrenaline.2070

These are responsible for the fight or flight response.2091

If a person or an animal is...there is a threat, somebody is chasing you, your body will release epinephrine and norepinephrine.2099

And what that is going to do is give you what you need to either fight the threat or run away from it.2111

And what you are going to need to do that? What you are going to need more oxygen, more sugar, more energy.2116

So, what is going to happen is an increase in heart rate, increase in blood pressure. Bronchodilation open up the airways, get more oxygen in.2124

Blood will be shunted to the skeletal muscles so that you can run or fight. Glucose levels will increase.2138

The pupils will dilate, so that is the fight or flight response.2147

Next, we are going to discuss the thyroid gland, which I mentioned as an example early in the lecture.2156

The thyroid gland is located in the neck, and it produces thyroxine and calcitonin.2162

So, recall that the anterior pituitary releases thyroid-stimulating hormone, which acts on the thyroid to promote the release of thyroxine.2170

Now, I am going to talk a little bit about some terminology that you will see.2185

We are focusing on thyroxine, but there is another hormone released by the thyroid gland.2187

The other name for thyroxine is T4, and the reason it is called T4 is there are 4 iodine atoms in it.2192

There is a second hormone produced by the thyroid gland called T3. As you can imagine, it has three iodine atoms.2201

Mostly, what the thyroid produces is T4, thyroxine, but in its target cells, that T4 is usually converted to T3.2211

For simplicity, I am just going to talk about thyroxine, T4, but this converts to T3; and then, that has an action on target cells.2219

The action of thyroxine ends up being to increase the metabolism.2231

Because iodine is required to make thyroid hormones, T3 and T4, a lack of iodine results in a condition called a goiter.2241

If there is iodine deficiency, lack of iodine, the result can be goiter, and in goiter, the individual with the condition will have a very enlarged thyroid gland.2251

In the U.S. for example, iodine is added to salt to help prevent iodine deficiency.2264

To understand the effects of thyroid hormone, let's look at the extreme cases.2273

Let's say somebody has too much thyroid hormone, and the result is a condition called hyper - so high thyroid - hyperthyroidism.2277

Their metabolism is going to be really increased, and the symptoms that they will get are they are going to be very hot.2292

They are going to lose weight. They might feel anxious.2304

Their heart is going faster. They might even have palpitations, problems sleeping2308

They are really hyped up, and thyroid increases the metabolism; but if that goes too far, too much, then, we can have some negative symptoms result.2313

Graves' disease is a cause of hyperthyroidism. It is actually an autoimmune disease.2324

What happens is there is an antibody that mimics TSH. Remember that TSH stimulates the thyroid to produce thyroxine.2332

Now, normally, the pituitary will not release TSH unless there is a stimulus like a person's cold.2348

And their body says "OK, we need to increase the metabolism here".2354

But this antibody is not under the normal controls of the body like TSH release would be.2359

It is an imposter but it is still can act on the thyroid and cause it to release thyroxine the way normal TSH would.2364

As a result, the person's metabolism is increased.2373

The other possibility is hypothyroidism, and in this case, we have decreased levels of thyroid hormone.2379

There is also an autoimmune disease that can cause this.2394

It has different mechanism in the opposite situation with Graves' where the thyroxine is not being produced in high enough levels.2397

These individuals, instead of losing weight, they will gain weight. They will feel cold.2406

They might have hair loss, lethargic. They will sleep too much.2413

They might become depressed. So, everything is decreased instead of increased like with hyperthyroidism.2420

The second hormone that you should be familiar with regarding the thyroid gland is calcitonin, and calcitonin decreases blood calcium level.2430

It does this by stimulating, so it stimulates the uptake of calcium by the bones.2448

So, the bones are reservoir to store calcium. Therefore, if blood calcium levels are high - so this is in the blood - then, calcitonin is released,2461

uptake of calcium by the bones, also, calcitonin stimulates the loss of calcium via the kidney and loss of calcium via the kidney, so it is excreted out.2477

Then, the result is blood calcium levels will be decreased, so it helps to maintain homeostasis in that way.2492

There is a set of four glands located right behind the thyroid gland in the neck, and these are the parathyroid glands.2505

The hormone they secrete is called parathyroid hormone or PTH.2513

PTH has the opposite effect of calcitonin, so we have the parathyroids. They release PTH, and PTH is going to increase calcium levels in the blood.2520

How does it do that? Well, what PTH actually does is stimulates the breakdown of bone to release calcium.2541

A second action is to stimulate the reabsorption of calcium in the kidney.2561

Calcitonin was causing calcium to be stored in the bone and was causing calcium to be lost by the kidneys,2577

so getting rid of calcium or storing it to decrease blood calcium levels.2591

Here is the opposite: increasing blood calcium levels by breaking down bone and having the kidney hold on to or reabsorb calcium.2597

It is a physiological antagonist, PTHs to calcitonin.2606

The last set of endocrine glands that we are going to talk about are the ovaries and the testis.2613

And these release the sex hormones: estrogen, progesterone and testosterone.2617

Now, we are going to again talk about this in more detail under the separate set of lectures on reproduction.2622

But, for completeness to just introduce this topic as part of the endocrine system, starting with the ovaries,2630

the ovaries produce estrogen and progesterone.2638

As it says right here, estrogen is responsible for the development of the secondary sex2647

characteristics in females during puberty and maintains those characteristics later on.2654

Secondary sex characteristics are not directly involved in reproduction, so it is not the actual production of sperm or egg.2659

But, secondary sex characteristics have to do with attracting a mate or their characteristics that are different in males and females.2670

So, that is part of estrogen's job is to cause the development of secondary sex characteristics during puberty2677

in females such as stimulating breast development also, a change in shape of the pelvis in females.2685

Estrogen plays a role on the menstrual cycle.2693

Progesterone, I just remember pro-gestation because it is a hormone that maintains pregnancy. It prevents the uterine lining from shedding.2697

It promotes an environment that will allow for the embryo and fetus to survive.2705

The testis secrete testosterone.2712

Testosterone stimulates the development of secondary sex characteristics in males such as facial hair, deepening of the voice and increase muscle mass.2715

And again, we are going to talk about more functions and how the progesterone, estrogen, testosterone work in this section on reproduction.2726

Now, though, we are going to go on and do some review on the endocrine system.2738

Example one: Match the following hormones with their descriptions.2742

Parathyroid hormone is the first one, and let's look at the choices:2748

Parathyroid hormone increases the metabolic rate, increases calcium level in the blood, stimulates the fight or flight response, stimulates uterine contraction.2753

Remember parathyroid gland is located near the thyroid in the neck, and PTH or parathyroid hormone causes an increase in calcium level.2766

It causes bone to breakdown and release calcium into the blood, so the answer here is B.2778

Two: oxytocin. We have choice of increase the metabolic rate, stimulate the fight or flight response or stimulate uterine contractions.2785

And in fact, oxytocin, which is produced by the hypothalamus and stored in2795

the posterior pituitary does stimulate uterine contractions allowing for child birth.2800

Thyroxine: as we talked about, thyroxine increases the metabolic rate, which leaves us with epinephrine and norepinephrine,2807

which are secreted by the adrenal medulla and stimulate the fight or flight response.2817

Example two: why is the pancreas considered to be both an endocrine organ and an exocrine organ?2827

Well, let's start with exocrine. Remember that an exocrine organ secretes substances via ducts.2834

In its function as part of the digestive system, the pancreas secretes digestive enzymes such as lipases and amylases through the pancreatic duct.2847

Therefore, it is an exocrine organ.2868

In its role as an endocrine organ, the pancreas also secretes hormones directly into the blood stream.2879

And these hormones involve the regulation of glucose. In the islets of Langerhans are produced insulin and glucagon.2892

Therefore, the pancreas is both an exocrine gland and an endocrine gland.2904

Example three: describe how the opposing actions of insulin and glucagon regulate the level of glucose in the blood.2910

Remember that these are antagonistic hormones. They cause opposite responses in the body.2918

Let's start out with when the blood glucose is high, so blood glucose increases.2929

If it is too high, the pancreas will release insulin. Insulin will cause uptake of glucose by cells, so it takes that glucose out of circulation.2937

The result by picking up the glucose and some of it is stored in the liver as glycogen2955

is going to be that the blood glucose level drops, so decreased blood glucose.2962

Let's say that the blood glucose level becomes too low, so low blood glucose. The result is going to be that the pancreas will release glucagon.2970

Glucagon is going to stimulate the breakdown or the hydrolysis of glycogen in the liver.2988

Glucose will be released into the blood stream. Therefore, blood glucose will go up.2999

So, between the two, glucose can be very tightly regulated.3008

Glucose gets a little too high, insulin is released. Glucose gets a little too low, glucagon is released.3012

Example four: symptoms of Cushing's syndrome include weight gain, thinning of the skin and easy bruising.3026

The cause is an increased level of cortisol in the blood.3034

Over secretion of hormones from which gland could result in Cushing's syndrome?3038

Well, recall that cortisol and other corticosteroids are released by the adrenal cortex.3042

Therefore, if an individual had over-secretion of hormones by the adrenal cortex,3051

they would have increased cortisol level and could exhibit these symptoms.3060

That concludes this discussion on the endocrine system here at Educator.com.3066

Thank you for visiting.3071

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